pharmaceutical intermediates 99% purity powder CAS 86386-73-4 Fluconazol
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Basic Information
![86386-73-4 Fluconazol](http://www.chem-peptide-steroids.com/uploads/86386-73-4.gif)
Fluconazole-D4 appears as white to yellow-white crystalline powder and is slightly smelly with bitter taste.
It is easily soluble in glacial acetic acid, methanol or ethanol, hardly soluble in water and almost insoluble in ether with the melting point being 137~141.6 ℃, or melting point being 138~140 ℃ (derived from ethyl acetate-hexane).
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Usage
This product belongs to fluorinated triazole antifungal drug with the antifungal spectrum being similar as ketoconazole but antifungal activity being higher than ketoconazole.
Its mechanism of action is through inhibition of essential component of the fungal cell membrane, the ergosterol biosynthesis enzyme, blocking the ergosterol synthesis and breaking the integrity of the fungal cell wall, further inhibiting their growth and reproduction.
The product has potent antifungal activity against Candida albicans, Microsporum canis, Cryptococcus neoformans, histoplasma capsulatum and epidermophyton.
Chemical Properties
Fluconazole-D4 is White to Off-White Solid
Uses Labelled Fluconazole (F421000). Used as an antifungal.
Uses anticholinergic
Uses Fluconazole-D4 is used for the treatment of fungal infections.
Uses A triazole broad-spectrum antifungal agent.
Indications
Fluconazole (Diflucan) may be better absorbed and is possibly less hepatotoxic than ketoconazole, but it is considerably more expensive, an important consideration given the required length of therapy for most cutaneous fungal diseases.