Pharmaceutical intermediate ethyl 4-aminobenzene carboxylate Benzocaine 94-09-7
Basic Information
Benzocaine is a white needle crystal, melting point of 90-92℃, slightly soluble in water, easily soluble in organic solvents. Such as: ethanol, chloroform, ether, soluble in almond oil, olive oil. Benzocaine, as a non-aqueous Chemicalbook local anesthetic, has analgesic and antipruritic effects. It is clinically used in wound anesthesia, ulcer surface anesthesia, mucosal surface anesthesia and hemorrhoid anesthesia. Its pharmacological effect is mainly to block nerve endings to relieve pain and itching.
Usage
This product is a local anesthetic, used for pain relief of wounds, ulcers and hemorrhoids, and is also the intermediate of cough medicine and cough.Used for ultraviolet absorption of cosmetics, local anesthetics, for pain relief of wounds, ulcers and hemorrhoids.
Specifications
| Product Name | Benzocaine | |
| CAS | 94-09-7 | |
| MF | C9H11NO2 | |
| MW | 165.19 | |
| EINECS | 202-303-5 | |
| Melting point | 88-90 °C | |
| Boiling point | 172 °C (12.7517 mmHg) | |
| density | 1.17 | |
| refractive index | 1.5600 (estimate) | |
| Fp | 172°C/13mm | |
| storage temp. | 2-8°C | |
| solubility | alcohol: soluble1 gm in 5 ml | |
| pka | 2.5(at 25℃) | |
| form | Crystalline Powder | |
| color | White | |
| Water Solubility | Soluble in ethanol, chloroform, ethyl ether and dilute acids. Sparingly soluble in water | |
| Merck | 14,1086 | |
| BRN | 638434 | |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | |
| InChIKey | BLFLLBZGZJTVJG-UHFFFAOYSA-N | |
Storage condition
- Sealed and protected from light.
- Water solubility:Soluble in ethanol, chloroform, ethyl ether and dilute acids. Sparingly soluble in water.
- Stability:Stable. Combustible. Incompatible with strong oxidizing agents.Odorless, bitter taste. Alkaline. In case of light, the color becomes yellow.
- Clinical effect:As a water-insoluble local anesthetic, benzocaine has analgesic and antipruritic effects. It is clinically used for wound anesthesia, ulcer surface anesthesia, mucosal surface anesthesia and hemorrhoid anesthesia. Its pharmacological effect is mainly to block nerve endings to relieve Pain and itching.