GHRP-6 CAS: 87616-84-0 Kukula kwa hormone kutulutsa peptide
Kugwiritsa ntchito
Growth hormone-release peptide 6 (GHRP-6) (developmental code name SKF-110679), yomwe imadziwikanso kuti kukula kwa hormone-release hexapeptide, ndi imodzi mwa ma analogue angapo a met-enkephalin omwe amaphatikizapo D-amino acid osakhala achilengedwe, adapangidwira kukula kwa hormone-kutulutsa ntchito ndipo amatchedwa kukula kwa secretagogues.Alibe ntchito ya opioid koma ali olimbikitsa kwambiri kutulutsa kwa hormone.Ma secretagogues awa ndi osiyana ndi kukula kwa timadzi timene timatulutsa timadzi tating'onoting'ono chifukwa sagawana ubale wotsatizana ndipo amapeza ntchito yawo poyambitsa cholandilira chosiyana kwambiri.Cholandilira ichi poyambilira chimatchedwa kukula kwa hormone secretagogue receptor, koma chifukwa cha zomwe zapezedwa pambuyo pake, timadzi ta ghrelin tsopano timadziwika kuti receptor's natural endogenous ligand, ndipo idatchedwanso kuti ghrelin receptor.Chifukwa chake, ma GHSR agonists awa amakhala ngati ma ghrelin mimetics.
Zapezeka kuti pamene GHRP-6 ndi insulini zimayendetsedwa nthawi imodzi, GH kuyankha kwa GHRP-6 kumawonjezeka.Komabe, kudya zakudya zama carbohydrate ndi/kapena zakudya zopatsa thanzi, kuzungulira zenera la oyang'anira a secretagogues a GH kumasokoneza kwambiri kutulutsidwa kwa GH.Kafukufuku waposachedwa pa mbewa zabwinobwino adawonetsa kusiyana kwakukulu kwa kapangidwe ka thupi, kukula kwa minofu, kagayidwe ka glucose, kukumbukira komanso ntchito yamtima mu mbewa zomwe zimayendetsedwa ndi GHRP-6.Pali mafunso ambiri okhudza gulu latsopanoli.