GHRP-2/Pralmorelin CAS:158861-67-7 d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide
Kugwiritsa ntchito
Pralmorelin (INN) (dzina la malonda GHRP Kaken 100; Mayina akale a chitukuko cha KP-102, GPA-748, WAY-GPA-748), yomwe imadziwikanso kuti pralmorelin hydrochloride (JAN) ndi pralmorelin dihydrochloride (USAN), makamaka, Kukula. Hormone yotulutsa Peptide 2 (GHRP-2), secretagotor ya kukula kwa hormone (GHS), imagwiritsidwa ntchito ngati njira yodziwira matenda ndipo imagulitsidwa mu mawonekedwe a mlingo umodzi wopangidwa ndi Kaken Pharmaceutical waku Japan pofuna kuyesa kuchepa kwa hormone (GHD).
Pralmorelin ndi mankhwala opangira peptide okhala ndi zochitika zapakamwa.Mwachindunji, ndi analogue ya methoxyenkephalin ndi amino acid sequence D-Ala-D -(β-naphthyl) -ala-trp-d-phe -Lys-NH 2. Imakhala ngati auxin yotulutsa peptide / kukula kwa hormone secretin receptor ( GHSR) agonist ndipo ndiye mankhwala oyamba amtundu wake kuti alowetsedwe kuchipatala.Kuwongolera mwachangu kwa mankhwalawa kumawonjezera kwambiri kuchuluka kwa plasma kukula kwa hormone (GH) ndipo kumapangitsa njala ndikuwonjezera kudya mwa anthu.
Pralmorelin akuphunziridwanso za GHD ndi kutalika kwaufupi (pituitary dwarfism) ndipo adalowa m'mayesero azachipatala a gawo lachiwiri pazowonetsa izi, koma sanapangepo msika.Izi zitha kukhala chifukwa kuthekera kwa pramoline kukulitsa milingo ya GH ya plasma ndikotsika kwambiri mwa odwala GHD kuposa anthu athanzi.
