99.3% Purity YK-11 SARMs Steroids Otaya Mafuta Ovuta M'mimba CasNO.431579-34-9
Zambiri za YK-11
Dzina la Mankhwala: (17a,20E) -17,20-[(1-Methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna- 4,20-diene-21-carboxylic Acid Methyl Ester
Mawu ofanana: (17a,20E) -17,20-[(1-Methoxyethylidene) bis(oxy)]-3-oxo-19-norpregna- 4,20-diene-21-carboxylic Acid Methyl Ester;YK11 ((17α, 20E) -17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-;DNA (Terrabacter strain YK11 16S rRNA gene fragment);GenBank AB070463
CAS: 431579-34-9
YK-11Kufotokozera
SARMS kapena kusankha androgen receptor modulators amadziwika bwino popereka zotsatira zofanana za kukula kwa minofu monga anabolic steroids koma popanda zotsatira zoipa zomwe zimabwera ndi zotsirizirazo.Asayansi aku Japan akuyesa kuyesa kwa SARM yatsopano yotchedwa YK11 yomwe imanenedwa kuti ndi yamphamvu kwambiri kuposa onse, ngakhale yamphamvu kwambiri kuposa ma steroid akale monga DHT.YK11 imakhulupirira kuti ndi SARM ndipo imatulutsa zotsatira za myostatin nthawi yomweyo.
Kodi YK11 Imagwira Ntchito Motani?
Mu 2011, Yuichiro Kanno wa ku yunivesite ya Toho adasindikiza zotsatira za kafukufuku woyamba pa YK11, kutsimikizira kuti gulu losowa linali SARM.
YK11 imadziphatika ku AR (androgen receptor), koma imangoyambitsa njira zomwe zimatsogolera ku zotsatira zachikhalidwe za androgens monga kukula kwa tsitsi la thupi ndi prostate ndi kuwonjezereka kwaukali - pamlingo woletsedwa.
Ma SARMS ambiri amakhala ndi zotsatira zochepa za androgenic, koma nthawi zambiri amakhala ndi zotsatira zochepa za anabolic zikafananizidwa ndi testosterone.Koma, izi sizichitika kwa YK11 monga momwe zafotokozedwera mu Biological and Pharmaceutical Bulletin mu 2013.
Kanno adayesa ma cell a minofu ya C2C12 osati nyama za labu kapena anthu.Zapezeka kuti maselo a minofu amapanga zinthu zambiri za anabolic ngati akuwonekera ku 500 nmol (nanomoles) YK11 kusiyana ndi ngati mumatulutsa maselo amtundu womwewo ku 500 nmol DHT.
YK11 imapangitsa maselo a minofu kupanga follistatin yambiri (kuposa DHT imachitira) - myostatin inhibitor yamphamvu.YK11 imagwira ntchito kudzera mu cholandilira cha androgen.
Ndi zomwe zanenedwa, YK11 ikhoza kukhala yabwino ngati testosterone ponena za kulimbikitsa minofu, koma kuchotsa zotsatira zowononga.
YK-11CERTIFICATE YA KUSANGALALA
Dzina la malonda | YK11 | ||
CAS No. | 431579-34-9 | Kupaka Kwakunja | |
Tsiku lopanga | 2017.09.05 | Alumali moyo | zaka 2 |
Standard anatengera | M'nyumba khalidwe muyezo | ||
Zinthu zowunikira | Kufotokozera | Zotsatira | |
Maonekedwe | White ufa | White ufa | |
Kuyesa | ≥98.0% | 99.3% (HPLC) | |
Kutaya pa Kuyanika | ≤1.0% | 0.3% | |
Mapeto | Woyenerera |