The topic of anti-aging has become more and more popular in recent years, with various studies emerging in endlessly.
Every now and then, some research group discovers an anti-aging substance that could help us live to a hundred years.
We humans have a lifespan limit of 150 years, because telomeres shorten a little every two to three years, and cells can divide about 50 times, says Hafrick of telomere Theory.
There are also some optimistic experts say: the first person to live to 1000 years old, has been born, in our world, may be you oh.
With the development of biomolecular biology, we may one day discover the magic substance that will help us live longer.
So, live healthy, work hard to make money, and wait for the technology mature one day, maybe, you really can live a long life.
Today, I’m going to introduce you to some of the most promising anti-aging supplements that are recognized, and take a look at a few that you’ve seen.
1. Epitalon
Epitalon is a synthetic anti-aging peptide, produced from the amino acid chain alanine-glutamine-asparagine-glycine, which upregates telomerase activity in the body to help reduce the rate of aging.
Telomeres are like hard hats that protect DNA. Most chromosomes in the body have telomeres at both ends; The main function of telomerase is to help maintain the length of telomeres in the body.
Some diseases are associated with shorter telomeres, leading to faster aging; Epitalon can be used to treat diseases that cause premature aging, such as Bloom syndrome and Werner syndrome.
Epitalon also helps reduce the risk of diseases related to telomerase deficiency, such as diabetes, because insulin secretion is inhibited by telomerase deficiency.
The peptide may also have a positive effect on heart health and may help prevent heart disease; Scientists are studying its potential in treating tumors.
2: Curcumin
Turmeric is a highly Indian food ingredient, and curcumin is the most studied active ingredient in turmeric, with strong anti-inflammatory and antioxidant properties.
Studies have shown that curcumin activates sirtuins (deacetylases) and AMPK(AMP-activated protein kinase), which help slow cell aging and prolong life.
In addition, curcumin has been shown to combat cell damage and significantly extend the lifespan of fruit flies, roundworms, and mice; It can also delay the onset of age-related diseases and reduce the symptoms of age-related diseases
3: cannabinoid
The active compounds of cannabis, known collectively as cannabinoids, are a group of terpenoid phenolic compounds, the most famous of which are tetrahydrocannabinol (THC) and cannabidiol (CBD).
CBD can fight free radicals in skin cells, acting as an antioxidant and anti-aging agent. It is often added to skin care products and is often used to relieve chronic pain, with great results
4: spermidine
Spermidine is a natural component of sperm, and our bodies (both male and female) only produce about a third of it, with the rest coming from our diet.
Its food sources include: aged cheese, mushrooms, natto, green pepper, wheat germ, cauliflower, broccoli, etc.
Asians have higher levels of arginous acid in their diet, which may be related to their longer life.
Research on spermidine has been growing in recent years, and it has been found to have the following effects:
Extend healthy life span;
Improve the cognitive level of the elderly;
Neuroprotective effect;
Reducing all-cause mortality;
Lower blood pressure;
Induce autophagy and delay senescence;
It makes hair grow faster and nails stronger.
5: ketone body
One of the main reasons ketogenic diets are popular is weight loss and mental clarity.
When the body starts burning body fat, it produces ketone bodies, which provide clean energy to the brain and improve its performance.
Ketones have anti-aging properties, and studies have found that BHB (beta-hydroxybutyric acid) can promote cell division, prevent cell aging, and keep blood vessels and the brain young.
The body can produce keto bodies by avoiding carbohydrates, or it can take exogenous keto supplements to speed up the process and reduce the pain of the transition, known as “keto flu.”
Ketogenic diets, or taking exogenous keto supplements, can slow aging, improve cognitive performance, and help stave off neurodegenerative diseases like Alzheimer’s.
6: Dasatinib
As we age, some of our cells evade the immune system. These “surviving” cells don’t do what they were supposed to do, but they still burn energy.
Such “all food and no work” cells, also known as “zombie cells”, or senescent cells, accumulate over time, making the body function less efficiently.
Fasting, exercise and other healthy lifestyles trigger autophagy, which cleans out zombie cells.
Dasatinib, a chemotherapy drug used in the treatment of leukemia, can also effectively remove aging fat cells and reduce the secretion of pro-inflammatory cytokines in the body’s adipose tissue.
It is the first Senolytics drug to be discovered, a drug that selectively clears senescent cells by interfering with senescent cell signaling pathways, temporarily disabling SCaps (anti-apoptotic pathways).
Substances that can clear away senescent cells include PCC1 from the Chinese Academy of Sciences, as well as other ingredients like quercetin.
Post time: Feb-24-2023