GHRP-2/Pralmorelin CAS:158861-67-7 d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide
Whakamahinga
Pralmorelin (INN) (ingoa hokohoko GHRP Kaken 100; Nga ingoa waehere whanaketanga o mua KP-102, GPA-748, WAY-GPA-748), e mohiotia ana ano ko te pralmorelin hydrochloride (JAN) me te pralmorelin dihydrochloride (USAN), ina koa, Growth Ko te homoni e tuku ana i te Peptide 2 (GHRP-2), he homone secretagotor (GHS), ka whakamahia hei kaihoko taatai me te hokohoko i roto i te puka hanga kotahi-horopeta e Kaken Pharmaceutical o Japan mo te aromatawai i te korenga o te homoni tupu (GHD).
Ko te Pralmorelin he rongoa peptide waihanga me te mahi waha.Ko te mea motuhake, he rite ki te methoxyenkephalin me te raupapa waikawa amino D-Ala-D -(β-naphthyl) -ala-trp-d-phe -Lys-NH 2. Ka mahi hei auxin tuku peptide/growth hormone secretin receptor ( GHSR) agonist a ko ia te rongoa tuatahi o ona momo ka whakauruhia ki te whare haumanu.Ko te whakahaeretanga o te tarukino ka tino whakanui ake i nga taumata o te homoni tupu plasma (GH) me te pono ka whakapoipoi i te hiakai me te whakanui i te kai o te tangata.
Kei te akohia ano a Pralmorelin mo te GHD me te poto o te tinana (pituitary dwarfism) ka uru ki nga whakamatautau haumanu o te wahanga II mo enei tohu, engari i te mutunga kaore i eke ki te maakete.Na te mea ko te kaha o te pramoline ki te whakanui ake i nga taumata GH plasma he tino iti ake i nga turoro GHD i nga tangata hauora.
