Calcitonin salmon CAS 47931-85-1 Salmotonin Thyrocalcitonin
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Āhuatanga:
Ingoa noa | hāmana calcitonin | Ingoa Ingarihi | Haramona Calcitonin Acetate |
---|---|---|---|
nama CAS | 47931-85-1 |
Kiato | 1.5±0.1g/cm3 |
---|---|
tātai rāpoi ngota | C145H240N44O48S2 |
Te taumaha ngota | 3431.853 |
Papatipu tika | 3429.713379 |
PSA | 1558.81000 |
RangitakiP | -12.48 |
Nga ahuatanga o te ahua | paura |
Taupū Refactive | 1.677 |
Nga tikanga rokiroki | Kua hiritia, rongoa ki te -18ºC |
Te pumau | Karekau he pirau, karekau he tauhohenga morearea ki te whakamahia me te rongoa i runga i nga whakaritenga |
Te wairewa | 0.05 M waikawa ahetiki: 1 mg/mL, maamaa, kore tae |
Whakamahinga:
Ko te Calcitonin Salmon he homone polypeptide i hunahia e te repe ultimobranchial o te salmon.No te whanau pūmua rite ki te calcitonin ka taea te whakamahi ki te rongoa i te mate o Paget o te wheua, te osteoporosis postmenopausal (he koiwi pakarukaru ranei), he taumata teitei o te konupūmā i roto i te toto (hypercalcemia).Te ahua nei he rite tonu nga mahi ki nga calcitonins o te takenga mai i te maminga, engari he nui ake te kaha mo ia mg me te roa o te mahi.Ko te nuinga o te mahi ma te aukati i te resorption o te wheua osteoclastic, te whakaheke i te konupūmā serum, me te whakanui ake i te tangohanga renal o te phosphate, te konupūmā, te konutai konupora me te pāhare pāporo mā te whakaheke i te reabsorption tubular.
I roto i te tangata, he kaha ake te hamana calcitonin i tana tairitenga tangata.
He pai te awe a Calcitonin (haramona) ki te whakarereketanga o nga wheua me te kiato papatipu iwi na te mea he aukati i te mahi osteoclast.Ko te painga whai hua o te salmon calcitonin i roto i te maimoatanga o nga whati wheua osteoporotic he tika ano mo te whakatairanga i te waahanga cartilaginous o te whakaora pakaru me te mamae mamae.
Ka taea te whakamahi calcitonin salmon mo te calcitonin receptor / cAMP assay mo te aromatawai i te aroaro o nga kaiwhakawhiwhi calcitonin e whakaatuhia ana e te TRAP + pūtau. hāmana calcitonin (sCT) i runga i te arai mucosal pekitīlia i roto i nga kiore e pa ana ki te makariri + te ahotea aukati (CRS).