page_banner

products

Larazotide acetate CAS 881851-50-9

short description:


  • Common name: Larazotide Acetate
  • CAS No.: 881851-50-9
  • Molecular formula: C34H59N9O12
  • Molecular weight: 785.88536
  • Melting point: >231°C (dec.)
  • Package: Bottle,Bag,Carton,Drum
  • Delivery time: 3 days after receipt of payment
  • Express: DHL,UPS,FedEx,Postal and so on.(Ps:can according customers requirements)
  • Payment method: Bank transfer,Bitcoin,Western Union and so on
  • Product Detail

    Product Tags

    Contact me:

    Email : salesperson66@yeah.net

    whatsapp: +8619832408762

    wickr: fairyqf

    Skype:+8619832408762

     

    Characteristic:

    common name Larazotide Acetate English name Larazotide acetate
    CAS number 881851-50-9 molecular weight 785.88500
    molecular formula 34 H 59 N 9 O 12
    accurate mass 785.42800
    PSA 360.55000
    LogP 3.73650

    Usage:

    Larazotide acetate is an intestinal tight-junction regulator drug , previously known as Innovate Biopharmaceuticals before a merger,that is currently being tested in adult patients with celiac disease in a phase III clinical trial . This single-chain peptide is derived from human zonulin, a known modulator of tight junction permeability that has elevated intestinal tissue expression in patients with celiac disease . LA also shares structural similarities to the Vibrio cholerae zonula occludens toxin (Zot),   which is an enterotoxin that disrupts intercellular tight junction structure through actin polymerization and cytoskeletal modifications that result in increased intestinal permeability through intracellular signaling . Although LA has shown promise in clinical trials for patients with celiac disease,   recent studies using various animal injury models indicate a potential use for LA for other diseases because of its ability to regulate tight junctions.     This mini-review aims to provide a detailed source of current information on this octapeptide.

    证书

    包装


  • Previous:
  • Next:

  • Write your message here and send it to us