2-Fluoroamphetamine CAS NO :1716-60-5
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Consuetudinem
2-fluamphetaminum (2-FA) medicamentum incitamentum est in familia amphetaminum et quasi proprium medicamentum venditum est.2-Fluoroamphetaminum differt ab 3- et 4 -fluoroamphetamine in positione atomorum fluorinorum in annulo aromatico, faciendo eas isomers positionales inter se.Atomis hydrogenii cum atomis fluorinis in quibusdam compositis repositis ad faciliorem transitum obice sanguinis cerebri, sicut medicinae systematis nervosi centralis desideratum est, usus communis est datus hac substitutione concessionum ob debitam auctam in lipophilicitate.
pharmacologia
Anorexia dosis (50% inhibitionis attractio cibi intra 2 horas, ante horam 1 datam) = 15 mg/kg (mures; oralis).
Dosis analgesica (50% inhibitionis reactionis caudae) = 20 mg/kg (mus; ip).
Effectus pressurae sanguinis: 0.5 mg/kg (mures intravenous) potest sanguinem pressuram suscitare per 29 mm.