etiti ọgwụ 99% ntụ ntụ dị ọcha CAS 86386-73-4 Fluconazol
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Ozi bụ isi
Fluconazole-D4 na-egosi dị ka ọcha na odo-acha ọcha crystalline ntụ ntụ ma na-esitụ isi na uto ilu.
Ọ dị mfe soluble na glacial acetic acid, methanol ma ọ bụ ethanol, na-esighi ike soluble na mmiri na ọ fọrọ nke nta insoluble na ether na-agbaze ebe 137 ~ 141.6 ℃, ma ọ bụ agbaze ebe 138 ~ 140 ℃ (nke sitere na ethyl acetate-hexane).
Ojiji
Ngwaahịa a bụ nke fluorinated triazole ọgwụ antifungal nwere ụdịdị antifungal yiri ketoconazole mana ọrụ antifungal dị elu karịa ketoconazole.
Usoro ya bụ site na mgbochi nke akụkụ dị mkpa nke akpụkpọ ahụ cell fungal, ergosterol biosynthesis enzyme, na-egbochi njikọ ergosterol na imebi iguzosi ike n'ezi ihe nke mgbidi cell fungal, na-egbochi uto na mmepụta ha.
Ngwaahịa a nwere ike antifungal ọrụ megide Candida albicans, Microsporum canis, Cryptococcus neoformans, histoplasma capsulatum na epidermophyton.
Njirimara kemịkalụ
Fluconazole-D4 na-acha ọcha ma ọ bụ na-acha ọcha siri ike
Na-eji Fluconazole akpọrọ (F421000).A na-eji ya dị ka antifungal.
Na-eji anticholinergic
A na-eji Fluconazole-D4 eme ihe maka ọgwụgwọ nke ọrịa fungal.
Na-eji A triazole wide-spectrum antifungal agent.
Ngosipụta
Fluconazole (Diflucan) nwere ike ịmịnye ya nke ọma ma nwee ike ịbụ hepatotoxic dị ala karịa ketoconazole, mana ọ dị oke ọnụ karịa, nlebara anya dị mkpa nyere ogologo ọgwụgwọ achọrọ maka ọtụtụ ọrịa fungal akpụkpọ.