Nimetazepam CAS: 2011-67-8 hypnotic tranquilizer
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Nimetazepam bụ hypnotic na-eme ihe na-eme ihe, nke sitere na benzodiazepine.Ndị otu Hoffmann-La Roche mere ya nke mbụ na 1964.Ọ nwere ike hypnotic, mgbochi nchegbu, calming na skeletal muscle ntụrụndụ mmetụta.Nimetazepam bụkwa ọgwụ mgbochi mgbakasị ahụ dị irè.A na-ere ya dị ka mbadamba nkume 5-milligram akpọrọ Erimin, aha akara nke Sumitomo, nnukwu ụlọ ọrụ Japan mere ma ree ya.Japan bụ naanị mba na-emepụta nimetazepam n'ụwa.N'èzí Japan, Erimin dị n'ọtụtụ ebe ọwụwa anyanwụ na ndịda Ebe Ọwụwa Anyanwụ Eshia ma na-ejikarị ya eme ihe dị ka ọgwụgwọ oge dị mkpirikpi maka ndị nwere oké ehighị ụra nke ọma bụ ndị na-esiri ike ịrahụ ụra ma ọ bụ na-ehi ụra.Sumitomo akwụsịla ime Erimin kemgbe ọnwa Nọvemba 2015. Ọ ka dị ka ọnụọgụ ma ọ bụ Lavol.
Edere Nimetazepam n'ọtụtụ ebe na 1980 na 1990, ọkachasị na Japan, Malaysia, Brunei, Philippines, Thailand, Indonesia, Hong Kong na Singapore.Site na mmegbu na iri ahụ riri ahụ juru, ndenye ọgwụ maka ọgwụ adalatala nke ukwuu kemgbe 2005. A na-eji ya eme ihe n'ụzọ bụ isi dị ka ọgwụ mgbochi na ụmụaka.A ka na-ejikwa ya n'ọnọdụ kachasị njọ na nke na-agwụ ike nke ehighị ụra nke ọma na Ntọala ụlọ ọgwụ ma ọ bụ ọgwụgwọ ụlọ ọgwụ dị mkpirikpi.Maka ebumnuche a, a na-eji ọgwụ ihi ụra benzodiazepines Esazolam na nitrazepam mee ihe ugboro ugboro karịa nitrazepam.Ọgwụ mgbochi ịda mbà n'obi dị ka trazodone na mirtazapine ma ọ bụ Zopiclone na zolpidem bụ ọgwụ ahịrị mbụ maka ehighị ụra nke ọma.
Ọ bụ ezie na ndenye ọgwụ nimetazepam ebelatala, iji ọgwụ eme ihe na-adị elu na Brunei, Singapore, Malaysia na Philippines.A na-ejikarị ya na methamphetamine na ecstasy, yana opioids (karịsịa heroin ma ọ bụ morphine).Nimetazepam nọ n'okpuru mmachibido iwu siri ike na Malaysia, nke mere ka ọgwụ ahụ dị ụkọ, mana ọtụtụ n'ime ọgwụ ndị a na-ere n'ahịa ojii n'okpuru aha Nimetazepam bụ adịgboroja.Diazepam na nitrazepam so na benzodiazepines a na-ejikarị eme ihe na mpaghara ahụ, n'ihi ya, a na-atụgharịkarị ma na-ere ha n'ahịa ojii, na-abụkarị nitrazepam.
Nmezepam arụrụ n'ụzọ iwu na-akwadoghị (nke a na-ere dị ka Erimin-5) juru ebe niile na mpaghara ahụ.Mmegbu nke nimetazepam gara n'ihu na-abawanye na 2010 niile.Njide nke mbadamba Erimin-5 arụpụtara n'ụzọ iwu na-akwadoghị dabara na ọdịdọ methamphetamine na Malaysia.A nwalere ọnụ ọgụgụ dị nta nke mbadamba Erimin-5 46 n'ụzọ iwu na-akwadoghị maka akụrụngwa anụ ahụ na kemịkal ha.Ihe na-arụsi ọrụ ike, dopant, isi mmiri na-esiji, na agba bụ njirimara kemịkalụ nke mbadamba nkume ahụ.Nsonaazụ gosiri na Nimetazepam bụ ihe na-arụkarị ọrụ n'ime ọtụtụ mbadamba mbadamba ejidere.Achọpụtara lactose dị ka isi ihe na-esi nri n'ọtụtụ nlele, mannitol sochiri ya wee bụrụ dicalcium phosphate dihydrate.Ahụrụ odo ọdịda anyanwụ n'ọtụtụ nlele pill, ejiri ya naanị ya ma ọ bụ jikọtara ya na akwa ndị ọzọ (dịka tartar na Lichenol 4R) iji nye pill ahụ ka ọ bụrụ peach/agba oroma.Mbadamba akwụkwọ ndụ akwụkwọ ndụ dị na nlele ahụ nwere agba anụnụ anụnụ na tatar na-egbuke egbuke.Diazepam bụ isi ọgwụ na-egbochi nchekasị ma bụrụ ihe na-arụ ọrụ na naanị otu mbadamba 46.Achọpụtara Nitrazepam, ọgwụ na-eme ka ahụ dị ike na hypnotic na ọgwụ nne na nna nke nitrazepam, bụ nke abụọ, na caffeine bụ isi ihe jikọtara na mbadamba atọ.
Na 2003, Singapore weghaara mbadamba 94,200 Erimin-5.Ụlọ nyocha nke Central Narcotics Board (CNB) mere ule na mbadamba nkume na nsonaazụ gosipụtara na ha bụ nitrazepam n'ezie.