China na-enye Lidocaine CAS 137-58-6 na ọnụ ahịa kacha mma
Ozi bụ isi
soluble na ethanol, ether, benzene, chloroform na mmanụ, a na-apụghị ịsacha na mmiri.Hydrochloride base nke a na-ejikarị, lidocaine hydrochloride (C14H22N2O·HCl, [73-78-9]) bụ ntụ ntụ kristal ọcha.Ebe agbaze bụ 127-129 ℃, na ebe agbaze nke monohydrate bụ 77-78 ℃.Na-agbaze nke ukwuu na mmiri, 0.5% aqueous pHO4.0-5.5.Enweghị isi, ụtọ hemp na-elu ilu.
Ojiji
Ngwaahịa a bụ ọgwụ anestetiiki mpaghara amide.A na-eji ya eme ihe n'ọtụtụ ebe na nhụsianya elu, nhụsianya infiltration, anesthesia conduction na epidural anesthesia.LD50 nke lidocaine hydrochloride bụ 290mg/kg.
Ngwa ụlọ ọgwụ na-agụnye nhụsianya infiltration, epidURAL anesthesia, anesthesia n'elu (gụnyere anesthesia mucosal n'oge thoracoscopy ma ọ bụ ịwa ahụ abdominal), na mgbochi akwara.Enwere ike ịgbakwunye epinephrine na anestetiiki iji mee ka oge anesthesia dị ogologo ma belata mmetụta ndị dị ka nsị site na lidocaine.
A pụkwara iji Lidocaine na-agwọ ọrịa ventricular arrhythmias mgbe nnukwu myocardial infarction, gụnyere mgbochi ventricular akaghi aka, tachycardia ventricular, arrhythmias ventricular kpatara nsị digitalis, ịwa ahụ obi na catheterization obi, gụnyere ventricular premature contractions, ventricular tachycardia.A na-ejikwa ya na ndị ọrịa nwere ọnọdụ epilepticus bụ ndị na-adịghị anabata ọgwụ mgbochi ndị ọzọ yana maka mgbakasị mpaghara ma ọ bụ intraspinal.Ọ naghị adị irè megide arrhythmias supraventricular.
Nkọwapụta
| Aha ngwaahịa | Lidocaine |
| CAS | 137-58-6 |
| MF | C14H22N2O |
| MW | 234.34 |
| EINECS | 205-302-8 |
| Ebe mgbaze | 66-69°C |
| Ebe esi nri | bp4 180-182°;bp2 159-160° |
| njupụta | 0.9944 (atụmatụ siri ike) |
| index refractive | 1.5110 (ọnụego) |
| Fp | 9 ℃ |
| nchekwa okpomọkụ. | Ụlọ ahịa na RT |
| solubility | ethanol: 4 mg / ml |
| pka | pKa 7.88 (H2O) (ihe dị ka) |
| ụdị | ntụ ntụ |
| agba | Ọcha ruo ntakịrị odo odo |
| Mmiri Solubility | ọ fọrọ nke nta ka ọ ghara ịsacha ya |
| Merck | 14,5482 |
| Nkwụsi ike: | Kwụsie ike.Ekwekọrịtaghị na ndị ọrụ oxidizing siri ike. |
| InChiKey | NNJVILVZKWQKPM-UHFFFAOYSA-N |
| Ntuziaka dataBase CAS | 137-58-6(CAS DataBase ntụaka) |