Calcitonin salmon CAS 47931-85-1 Salmotonin Thyrocalcitonin
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Njirimara:
Aha nkịtị | salmon calcitonin | Aha bekee | Salmon Calcitonin Acetate |
---|---|---|---|
Nọmba CAS | 47931-85-1 |
Njupụta | 1.5±0.1g/cm3 |
---|---|
Usoro ihe omimi | C145H240N44O48S2 |
Ibu molekụla | 3431.853 |
Ezi uka | 3429.713379 |
PSA | 1558.81000 |
LogP | -12.48 |
Àgwà mpụta | ntụ ntụ |
Ntụgharị ntụgharị | 1.677 |
Ọnọdụ nchekwa | Akara akara, chekwaa na -18 ºC |
Nkwụsi ike | Enweghị ire ere, enweghị mmeghachi omume dị ize ndụ amaara ma ọ bụrụ na ejiri ya ma chekwaa ya dịka nkọwapụta |
Mmiri solubility | 0.05 M acetic acid: 1 mg/mL, doro anya, enweghị agba |
Ojiji:
Calcitonin Salmon bụ homonụ polypeptide nke ultimobranchial gland nke salmon zoro ezo.Ọ bụ nke ezinụlọ protein dị ka calcitonin ma enwere ike iji ya gwọọ ọrịa Paget nke ọkpụkpụ, postmenopausal osteoporosis (ọkpụkpụ na-esighi ike ma ọ bụ nke na-agbaji agbaji), ma ọ bụ nnukwu calcium n'ime ọbara (hypercalcemia).Ọ dị ka ọ nwere omume yiri calcitonins sitere na mammalian, mana ike ya kwa mg ka ukwuu yana ọ na-ewe ogologo oge nke ime ihe.Ọ na-arụ ọrụ tumadi site na igbochi osteoclastic resorption ọkpụkpụ, ibelata serum calcium, na ịba ụba excretion nke phosphate, calcium, sodium magnesium na potassium site na ibelata tubular reabsorption.
N'ime ụmụ mmadụ, salmon calcitonin na-arụ ọrụ karịa analog nke mmadụ.
Calcitonin (salmon) na-emetụta ngbanwe ọkpụkpụ na njupụta ọkpụkpụ n'ihi mmetụta ya na-egbochi ọrụ osteoclast.Mmetụta bara uru nke salmon calcitonin na ọgwụgwọ ọkpụkpụ ọkpụkpụ osteoporotic bụkwa n'ihi nkwalite nke cartilaginous na-agwọ ọrịa na-agwọ ọrịa na mgbu mgbu.
Enwere ike iji salmon calcitonin mee ihe maka nyocha nke calcitonin receptor / cAMP maka nyochaa ọnụnọ nke ndị na-anabata calcitonin nke mkpụrụ ndụ TRAP + gosipụtara. A pụkwara iji ngwaahịa ahụ dị ka ihe nyocha maka ọmụmụ ihe yana atụnyere mmetụta nke peptide metụtara calcitonin gene (CGRP) na. salmon calcitonin (sCT) na mgbochi mucosal gastric n'ime oke ndị ekpughere na oyi + mgbochi nrụgide (CRS).