SARM SR9011 Pharmaceutical Raw Powder Rau Boosting Exercise Endurance CAS 1379686-30-2

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Khoom npe:TIAB SA 9011
Yam khoom:TIAB SA 9009
CAS:1379686-29-9
Qhov tsos:Dawb hmoov
Kev siv:Lub Tsev Kho Mob
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Lub teeb siab:sarms bodybuilding supplements, sarms steroids

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Product Detail

Khoom cim npe

SR9011 Cov ntsiab lus ceev

CAS Nr 1379686-29-9
Synonyms 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-
1-carboxamide
Cov roj formula: C23H31ClN4O3S
Molucelar hnyav 479.03524

TIAB SA 9011Kev piav qhia

SR9011 yog ib qho trifunctional methacrylate monomer uas muab tshwj xeeb adhesion rau hlau
substrate.

SR9011 raug pom zoo siv rau hauv peroxide kho coatings, sealants, thiab PVC-raws li plastisols.
Kev siv qib ntawm 5% mus rau 10% los ntawm qhov hnyav tau pom zoo.

SR9011 yog ib qho muaj zog thiab tshwj xeeb hluavtaws REV-ERB.Nws kuj muaj qhov zoo hauv vivo plasma / hlwb raug.
Lub nuclear receptors REV-ERB-α thiab REV-ERB-β ua lub luag haujlwm tseem ceeb hauv kev tswj cov lus qhia.
txhawb kev ua haujlwm ntawm cov metabolism hauv lub cev, ua kom lub cev ua haujlwm ntawm lub cev.Kev tswj hwm ntawm SR9011 hloov pauv
circadian tus cwj pwm thiab cov qauv circadian ntawm cov core moos gene qhia hauv hypothalami ntawm nas.
Lub circadian qhia qauv ntawm ib qho array ntawm metabolic noob nyob rau hauv daim siab, skeletal leeg thiab
Cov ntaub so ntswg adipose kuj tau hloov pauv, ua rau muaj kev siv zog ntxiv.Kev kho mob ntawm kev noj haus
Cov nas rog rog nrog SR9011 txo qhov rog los ntawm kev txo cov rog rog thiab ua kom zoo dua dyslipidaemia thiab hyperglycemia.Cov txiaj ntsig no qhia tau tias hluavtaws REV-ERB ligands uas pharmacologically phiaj
circadian atherosclerosis tuaj yeem ua rau muaj txiaj ntsig zoo hauv kev kho mob pw tsaug zog nrog rau cov kab mob metabolic.

Yuav siv SR9011 li cas?

Hauv vitro: SR9011 tau siv ntawm 5-10 μM concentration hauv vitro thiab hauv cellular assays.
Hauv vivo: IP kev tswj hwm ntawm SR9011 tau siv ntawm 100 mg / kg ib zaug lossis ob zaug hauv ib hnub rau 12-30
hnub hauv cov qauv nas sib txawv.

Synthesis ntawm SR9009 thiab SR9011

Cov tshuaj tau tsim los ntawm kev txo qis ntawm 5-nitro-2-thiophenecarboxaldehyde nrog 4-chlorobenzylamine thiab sodium triacetoxyborohydride yielded cov amine theem nrab.Ib qho kev txo qis thib ob nrog 1-Boc-pyrrolidine-3-carboxaldehyde yielded tertiary amine.Cov tshuaj no tau kho nrog trifluoroacetic acid kom tshem tawm cov pab pawg Boc-tiv thaiv, thiab tom qab ntawd cuam tshuam nrog ethyl chloroformate (SR9009) lossis pentyl isocyanate (SR9011) los muab cov khoom xav tau.

TIAB SA 9011COA

Yam khoom	Specification	Kev tshwm sim
Qhov tshwm sim	Ib qho ntxhiab tsw, yuav luag dawb los yog dawb hmoov	hla
Cov cim	Lub sijhawm khaws cia ntawm lub ncov loj yog lees paub rau RS	hla
Poob rau ziab	Tsis ntau tshaj 0.5%	0.33%
Kev ntsuam xyuas (HPLC)	Tsis pub tsawg tshaj 99.0%	99.59%
Ignition residue	Tsis ntau tshaj 0.1%	hla
Hnyav hlau	Tsis ntau tshaj 20 ppm	hla