Tom ntej: Pharmaceutical Intermediates 99% Purity hmoov CAS 86386-73-4 Fluconazol
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Cov ntaub ntawv yooj yim
Fluconazole-D4 tshwm li dawb mus rau daj-dawb crystalline hmoov thiab yog me ntsis tsw nrog iab saj.
Nws yog yooj yim soluble nyob rau hauv glacial acetic acid, methanol los yog ethanol, hardly soluble nyob rau hauv dej thiab yuav luag insoluble nyob rau hauv ether nrog lub melting point yog 137 ~ 141.6 ℃, los yog melting point yog 138 ~ 140 ℃ (los ntawm ethyl acetate-hexane).
Kev siv
Cov khoom no belongs rau fluorinated triazole antifungal tshuaj nrog cov tshuaj tiv thaiv kab mob zoo ib yam li ketoconazole tab sis cov tshuaj tiv thaiv kab mob siab dua li ketoconazole.
Nws cov txheej txheem ntawm kev ua haujlwm yog los ntawm inhibition ntawm qhov tseem ceeb ntawm cov kab mob fungal cell membrane, ergosterol biosynthesis enzyme, thaiv cov ergosterol synthesis thiab rhuav tshem kev ncaj ncees ntawm cov phab ntsa ntawm cov kab mob fungal, ntxiv inhibiting lawv txoj kev loj hlob thiab kev loj hlob.
Cov khoom muaj zog tiv thaiv kab mob tiv thaiv Candida albicans, Microsporum canis, Cryptococcus neoformans, histoplasma capsulatum thiab epidermophyton.
Chemical Properties
Fluconazole-D4 yog Dawb rau Off-White Solid
Siv cov ntawv sau npe Fluconazole (F421000).Siv raws li ib tug antifungal.
Siv cov tshuaj anticholinergic
Kev siv Fluconazole-D4 yog siv los kho cov kab mob fungal.
Siv A triazole broad-spectrum antifungal agent.
Cov lus qhia
Fluconazole (Diflucan) tuaj yeem nqus tau zoo dua thiab muaj peev xwm ua rau hepatotoxic tsawg dua li ketoconazole, tab sis nws tseem kim dua, qhov kev xav tseem ceeb uas yuav tsum tau siv ntev ntawm kev kho mob rau feem ntau cov kab mob fungal.