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Ntuj tsob nroj Extract CAS 51-34-3 Scopolamine

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  • Hom npe:Scopolamine
  • CAS Nr:.51-34-3 ib
  • MF:C17H21NO4
  • MW:303.35 Nws
  • EINECS:200-090-3
  • Melting point:59ºC ua
  • Boiling point:444.28°C (kev kwv yees kwv yees)
  • ceev:1.31 ib
  • Cia temp.:-20 ° C
  • Refractive Index:1.5022 (kwv yees)
  • solubility:Soluble nyob rau hauv dej, dawb soluble nyob rau hauv ethanol (96 feem pua).
  • pka:7.55-7.81 (ntawm 25 ℃)
  • daim ntawv:zoo
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  • Product Detail

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    Cov ntaub ntawv yooj yim

    51-34-3 ib

    Scopolamine(hyoscine) muaj nyob hauv ntau cov tswv cuab ntawm Solanaceae (piv txwv li, H. niger, Duboisia myoporoides, Scopolia spp., thiab Datura metel).Scopolamineusually yog cais los ntawm niam cawv uas tseem tshuav los ntawm kev sib cais ntawm hyoscyamine.

    Hyoscine yog lub npe laus rau cov alkaloid no, txawm hais tiasscopolamine yog lub npe lees paub hauv Tebchaws Meskas.Scopolamine yog levo tivthaiv ntawm cov racemic sib xyaw uas hu ua atroscine.Lub alkaloid yog racemized yooj yim nyob rau hauv lub xub ntiag ntawm dilute alkali.

    Cov alkaloid tshwm sim nyob rau hauv daim ntawv ntawm levorotatory, viscousliquid uas tsuas yog me ntsis soluble hauv dej tab sis solublein cawv heev, chloroform, lossis ether.Nws tsim crystalline salts nrog feem ntau cov kua qaub, nrog hydrobromide yog qhov ruaj khov tshaj plaws thiab nrov tshaj plaws.Ib qho tshuaj aqueous ntawm hydrobromide uas muaj 10% mannitol tau hais tias tsis tshua muaj kev puas tsuaj ntau dua li cov tshuaj tsis muaj kev tiv thaiv.

    Pharmacology

    Scopolamine butylbromide, hloov kho scopolamine, yog cov tshuaj tiv thaiv kab mob peripheral;nws tsis tsuas yog tuaj yeem ua rau cov leeg nqaij du, tab sis tseem thaiv cov ganglion thiab neuromuscular hlws ris thiab muaj qhov tsis muaj zog ntawm qhov chaw.Cov tshuaj no muaj zog ua rau lub plab hnyuv du spasm dua li atropine thiab anisodamine;Nws tuaj yeem xaiv txo cov kab mob plab, kab mob biliary, thiab tso zis ua kom cov leeg mob spasm thiab inhibit nws peristalsis.

    Scopolamine butylbromide muaj kev cuam tshuam tsawg dua rau lub plawv, cov menyuam kawm ntawv, thiab cov qog ua kua qaub, yog li nws tsis tshua muaj kev cuam tshuam hauv nruab nrab lub paj hlwb, kev nthuav dav, inhibition ntawm qaub ncaug secretion, thiab lwm yam kev phiv, uas tsis zoo li atropine.

    Scopolamine butylbromide yog ib qho antagonist ntawm M cholinergic receptor, nws cov tshuaj muaj txiaj ntsig zoo ib yam li atropine, tab sis nws muaj nws tus kheej cov yam ntxwv uas muaj txiaj ntsig zoo hauv kev txhim kho cov ntshav microcirculation.

    CAS Nr .: 94-15-5
    Levamisole
    Levamisole

    Kev siv

    1. Scopolamineyog siv rau kev xyaum tib yam qhia raws li atropine, tab sis nws yuav tsum tau muab sau tseg tias nws muaj ib tug sedative nyhuv ntawm lub cev muaj zog kev ua si, thiab nws raug pom zoo rau kev kho mob ntawm Parkinsonian cov tsos mob.

    2. cholinergic (ophthalmic).


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