Chaw tsim khoom 99% Purity Dawb Powder Antitumor Polypeptide Pharma Qib Cancer Research MELITTIN CAS 20449-79-0
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MELITTIN CAS 20449-79-0 Kev Siv:
Melitin yog lub ntsiab active ingredient ntawm muv venom.Beevenom yog ib hom pob tshab venom nrog cov ntxhiab tsw tsw ntxhiab los ntawm cov neeg ua haujlwm muv venom qog thiab cov qog ua haujlwm.Thaum nws ua txhaum, nws tawm ntawm tus stinger.Ntawm ntau yam ntawm muv venom, melittin muaj cov ntsiab lus siab tshaj plaws, suav txog li 50% ntawm qhov hnyav ntawm muv venom, thiab nws muaj kev ua haujlwm lom neeg.Melittin yog ib hom kab peptide uas muaj 26 amino acids, nrog ib tug txheeb ze molecular hnyav ntawm 2849. Melittin muaj kev lom zem ntau.Cov kev tshawb fawb tshuaj niaj hnub no tau pom tias nws muaj cov tshuaj tiv thaiv kab mob, tshuaj tua kab mob, inhibiting platelet aggregation, anti-AIDS thiab ntau lwm yam.Melittin tuaj yeem tsim cov nyhuv tua muaj zog ntawm ntau cov qog hlwb los ntawm cov txheej txheem sib txawv, thiab yog cov tshuaj tiv thaiv qog nqaij hlav zoo heev.
Melittin tuaj yeem cuam tshuam kev loj hlob thiab kev loj hlob ntawm ntau tshaj 20 hom kab mob Gram-zoo thiab tsis zoo, thiab tuaj yeem txhim kho cov kab mob tua kab mob ntawm sulfonamides thiab penicillins.Melittin rhuav tshem cov kab mob cell membrane los ntawm kev khi rau daim nyias nyias kom ua tiav lub hom phiaj ntawm bacteriolysis.Ob leeg melittin thiab nws cov 6 derivatives tuaj yeem hloov txoj haujlwm ntawm T lymphocytes kis los ntawm HIV, inhibit HIV replication, thiab txo cov kab mob ntawm tus kab mob.
- Kev tua neeg ncaj qha Hauv vitro thwmsim tau lees paub tias melittin muaj qhov pom tseeb tua cov kab mob ntawm ntau cov qog cell xws li osteosarcoma, qog noj ntshav ntawm zes qe menyuam, thiab glioma, thiab cov nyhuv tua tau zoo cuam tshuam nrog cov koob tshuaj.Melittin tuaj yeem tua cov qog hlwb thiab tiv thaiv kev loj hlob ntawm cov qog hlwb, thiab tsis muaj kev cuam tshuam rau kev loj hlob ntawm cov hlwb ib txwm muaj.Melittin tuaj yeem nkag mus rau hauv cov cell membrane ntawm K562 hlwb, tsim cov pores, txhawb Ca2 + inflow, ua kom cov concentration ntawm Ca2 + hauv hlwb, ua rau cell lysis, thiab ncaj qha tua K562 hlwb.Nws yog feem ntau ntseeg hais tias melittin dissolves mitochondrial membrane ntawm cov hlwb, inhibits ib txwm ua pa ntawm cov qog hlwb, rhuav tshem lawv aerobic ua pa muaj peev xwm, inhibits kev loj hlob ntawm qog nqaij hlav, thiab ncaj qha tua cov qog hlwb.
- Immunomodulatory effect Cellular tiv thaiv kab mob yog ib qho tseem ceeb tiv thaiv rau lub cev tiv thaiv qog thiab kis kab mob.Lub xeev ntawm lub cev lub cev tiv thaiv kab mob ua lub luag haujlwm tseem ceeb hauv kev tshwm sim thiab kev loj hlob ntawm cov qog.Txhim khu kev tiv thaiv kab mob ntawm tes tuaj yeem ua rau muaj qee yam tshuaj tiv thaiv qog.
- Induction ntawm qog cell apoptosis Apoptosis, tseem hu ua programmed cell tuag, yog cov txheej txheem ntawm tes lom neeg tswj los ntawm ntau yam noob.Yog li ntawd, apoptosis yog ib qho txheej txheem nquag, uas suav nrog kev ua kom muaj zog, kev qhia thiab kev tswj hwm ntawm cov noob caj noob ces.Cov kev tshawb fawb niaj hnub no tau pom tias ntau cov tshuaj chemotherapeutic tuaj yeem ua tiav cov hom phiaj kho mob los ntawm inducing apoptosis hauv cov qog nqaij hlav cancer.Seb puas yuav induce apoptosis tau dhau los ua ib qho ntawm cov txheej txheem rau kev tshuaj xyuas cov tshuaj tiv thaiv kab mob.
Melittin tuaj yeem cuam tshuam cov kev ua ntawm sPLA2 los ntawm ntau qhov chaw, thiab qhov inhibition ntawm sPLA2 kev ua hauv cov kua synovial ntawm RA cov neeg mob tuaj yeem ncav cuag 96%.Yog li, daim ntawv thov ntawm melittin tuaj yeem txo qhov kev loj hlob ntawm RA.
Sub-dose melittin tuaj yeem txo qis lysis tus nqi ntxiv rau cov hlwb.Cov txheej txheem tiv thaiv no yuav cuam tshuam nrog melittin txhawb nqa Ca2 + influx, stimulating intracellular signal transduction system thiab tiv thaiv protein synthesis.Nws tau pom zoo tias daim ntawv thov ntawm cov nqi tsim nyog ntawm melittin muaj qee yam txiaj ntsig hauv kev kho mob ntawm RA los ntawm Chemicalbook.Nyob rau hauv xyoo tas los no, cov kev tshawb fawb tau pom tias qhov sib txawv ntawm cov tshuaj melittin tuaj yeem cuam tshuam rau kev ua haujlwm ntawm tes los ntawm cov kab sib txawv thiab ua rau muaj ntau yam teebmeem lom neeg.Kev thov kom tsim nyog ntawm melittin yuav muab kev kho tshiab rau qee yam kab mob.
FAQ:
1.Hais txog lub sij hawm xa tuaj:
Peb yuav xa cov khoom tam sim ntawd thaum peb tau txais cov neeg siv khoom siv nyiaj. Ib txwm muaj Tshuag.
2. Hais txog Qauv:
Peb tuaj yeem muab cov qauv, tab sis xav tau raws li koj qhov ntau thiab tus nqi khoom.Yog tias cov khoom no kim heev, peb tsis xa cov qauv dawb, yog tias txhua yam zoo, peb tuaj yeem xa cov qauv, tab sis xav tau cov neeg siv khoom thauj khoom.
3.Hais txog Thauj Express:
Peb yuav siv peb cov kab tshwj xeeb rau kev thauj mus los, zoo li satiety, yog li tsis txhob txhawj.
4.About Service:
Peb yuav lav qhov kev cai clearance thiab se.We muab qhov rooj rau qhov rooj pab.
5. Hais Txog Kuv:
Kuv yog ib tus neeg muag khoom. Hu rau kuv Alice yog ok.Yog tias koj txaus siab rau qhov no lossis lwm yam khoom siv tshuaj, koj txhua tus tuaj yeem tiv tauj kuv dawb, Kuv yuav teb koj raws sijhawm.
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