High Purity Pharma API CAS 14769-73-4 Hydrochloride Levamisole Base
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Cov ntaub ntawv yooj yim
Txhais
A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole uas muaj S configuration.Nws yog siv (feem ntau raws li cov ntsev monohydrochloride) los kho cov kab mob cab kab mob hauv npua, yaj thiab nyuj thiab yav tas los siv hauv huma s ua ib qho tshuaj kho mob rau kev kho mob qog noj ntshav ntau yam.Nws kuj yog dav siv los ua tus neeg deev luag poj luag txiv rau coccaine.
Cov lus qhia
Levamisole (Ergamisol) yog ib qho tshuaj tiv thaiv kab mob uas tau pom los txhim kho T-cell muaj nuj nqi thiab kev tiv thaiv ntawm tes.Cov tshuaj txhim kho txoj sia nyob ntawm cov neeg mob uas muaj cov qog nqaij hlav hauv plab hnyuv loj thaum ua ke nrog 5-fluorouracil;lub mechanism ntawm qhov kev sib tshuam no tsis paub.Levamisole tsis muaj cov tshuaj tiv thaiv kab mob tiv thaiv kab mob qog noj ntshav lossis mob qog noj ntshav thiab tsis tau pom muaj txiaj ntsig hauv kev kho mob qog noj ntshav uas tsis yog mob qog noj ntshav.
Cov teebmeem loj ntawm levamisole yog xeev siab thiab anorexia.Cov tawv nqaij ua pob khaus, khaus, cov tsos mob xws li mob khaub thuas, thiab kub taub hau kuj tau pom.
Cov lus qhia
Levamisole (Ergamisol) yog Ameslikas tsim los ua cov tshuaj antihelminthic.Nws potentiates cov teebmeem stimulatory ntawm antigens, mitogens, lymphokines, thiab chemotactic yam ntawm lymphocytes, granulocytes, thiab macrophages.Nws tau pom tias nce T cell-mediated tiv thaiv kab mob.
Levamisole tau siv tau zoo hauv kev kho mob ntev.Nws kuj tau pom zoo siv nrog fluorouracil hauv kev kho mob qog noj ntshav hauv plab.
Kev siv
Siv Cov tshuaj lom neeg teb hloov pauv.
Siv Levamisole yog siv rau thawj zaug thiab theem nrab tiv thaiv kab mob, kab mob autoimmune, kab mob ntev thiab rov tshwm sim, plab hnyuv loj adenocarcinoma, helmintosis, thiab mob caj dab rheumatoid.Lub ntsiab lus ntawm cov tshuaj no yog decaris, tetramizole, thiab lwm yam.
Levimasole kuj yog ib qho tshuaj ntawm kev xaiv rau ascardiasis.Ntau qhov kev tshawb nrhiav pom tias ib koob tshuaj levamisole kho tau los ntawm 90 mus rau 100% ntawm cov neeg mob ascardiasis, tshwj xeeb tshaj yog cov kab mob A. duodenale.Nws tsis tshua muaj txiaj ntsig tiv thaiv ancylostomiasis thiab strongyloidiasis.Txawm li cas los xij, nws tsis zoo rau N. americanus.Nws zoo nkaus li tias nws muaj cov nyhuv gangliostimulating rau cov kab mob cab hauv ob qho tib si parasympathetic thiab sympathetic cheeb tsam.Tsis tas li ntawd, nws raug suav hais tias cov tshuaj no muaj cov nyhuv immunomodulatory rau cov kab mob hauv lub cev.Lub ntsiab lus ntawm cov tshuaj no yog decaris, solacil, ergamisol, tramisol, immunol, thiab lwm yam.
Kev siv tshuaj kho mob
Ascariasis Hookworm kab mob
Levamisole tau siv rau hauv kev mob caj dab rheumatoid thiab qee qhov lwm yam mob uas tau hais los teb rau nws txoj haujlwm immunomodulatory.
Kev kho muaj nuj nqi
Antiinflammatory
Antimicrobial kev ua haujlwm
Nws cov haujlwm tseem ceeb yog tawm tsam Asc.lumbricoides thiab hookworms.Kab mob tuag tes tuag taw thiab kis tawm hauv cov quav hauv ob peb teev.
Kev siv tshuaj
L-isomer ntawm tetramisole, muaj raws li monohydrochloride.D-isomer tsis muaj kev ua haujlwm anthelmintic.Nws yog soluble heev hauv dej thiab ruaj khov nyob rau hauv lub xeev qhuav.
Mechanism ntawm kev ua
Levamisole muaj cov haujlwm immunomodulating.Nws ntseeg tau hais tias nws tswj hwm cellular mechanisms ntawm lub cev tiv thaiv kab mob, thiab cov txheej txheem ntawm nws qhov kev ua haujlwm yuav cuam tshuam nrog kev ua kom muaj zog thiab kev loj hlob ntawm T-lymphocytes, nce tus lej ntawm monocytes thiab ua kom cov macrophages, thiab nrog rau kev ua kom muaj zog thiab hemotaxis ntawm neutrophylic. granulocytes.Levamisole kuj nthuav tawm cov tshuaj anthelmint.Nws kuj ua rau kom lub cev tag nrho cov kev tiv thaiv thiab rov kho T-lymphocyte thiab phagocyte muaj nuj nqi.Nws tseem tuaj yeem ua tiav qhov kev ua haujlwm ntawm immunomodulatory los ntawm kev ntxiv dag zog rau cov tshuaj tiv thaiv tsis muaj zog ntawm kev tiv thaiv kab mob ntawm tes, tsis muaj zog tiv thaiv, thiab tsis muaj kev cuam tshuam rau cov tshuaj tiv thaiv ib txwm muaj.