GrowTH HORMONE, HUMAN CAS: 12629-01-5 HGH
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Human Growthhormone (GH) yog ib qho saw hlau, tsis-glycated, 191 amino acid hydroglobulin nrog lub cev hnyav ntawm 21700Da thiab isoelectric pI ntawm 4.9.Muaj disulfide bonds ntawm cysteine residues ntawm qhov chaw 53 thiab 165 thiab ntawm qhov chaw 182 thiab 189. Kwv yees li 75% ntawm kev loj hlob hormone secreted los ntawm lub anterior pituitary caj pas eosinophils yog secreted nyob rau hauv daim ntawv ntawm molecular qauv, thiab lwm 5% mus rau 10% yog. secreted nyob rau hauv daim ntawv ntawm molecular hnyav 20kDa.Lub spontaneous secretion ntawm hGH tshwm sim nyob rau hauv paroxysmal daim ntawv ntawm nruab hnub thiab hmo ntuj, thiab feem ntau tshwm sim nyob rau hauv thawj zaug qeeb-yoj lub sij hawm pw tsaug zog tom qab physiological pw tsaug zog.Thaum nruab hnub, tus so zoo li txhawb kev tso tawm ntawm hGH, tab sis daim ntawv tso tawm ntawm hGH tau cuam tshuam los ntawm kev pub noj, yoo mov, kev tawm dag zog thiab kev ntxhov siab, tab sis lub suab nrov tsis hloov pauv.Lub secretion amplitude, zaus thiab tag nrho secretion ntawm hGH yog siab nyob rau hauv cov hluas, thaum cov neeg laus nyob rau qhov tsis sib xws.Cov yam ntxwv Tib neeg txoj kev loj hlob hormone prohormone yog tsim los ntawm kev loj hlob cov tshuaj hormones ib txwm muaj nyob rau hauv cov kab mob uas muaj feem xyuam rau cov teeb liab peptides.Cov prohormones faib nyob rau hauv lub puab phab ntsa ntawm cov kab mob lub hlwb, tso ib tug kawg khoom zoo tib yam rau lub ntuj kev loj hlob hormone rau hauv daim nyias nyias qhov chaw, thiab ces tsuas yog lub sab nrauv phab ntsa ntawm lub cell raug puas tsuaj rau sau, thaum lub sab hauv phab ntsa ntawm lub cell tseem tsis zoo. los xyuas kom meej tias tsis muaj cov kab mob me me ntawm cov kab mob sib kis ntawm cov khoom kawg.Cov ntaub ntawv kev nyab xeeb
