Sarm S4 Andarine Yellow hmoov
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Andarine (S-4) yog arylpropionamide-derived compound [S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide] ua ntej piav los ntawm Yin et al.los ua tus xaiv androgen receptor modulator (SARM).Andarine (S-4) tau pom los ntawm hauv vitro thiab hauv vivo kev tshawb fawb los ua ib qho zoo anabolic agonist, tsis muaj kev phiv cuam tshuam feem ntau cuam tshuam nrog anabolic-androgenic steroids, feem ntau cuam tshuam rau substrate affinity rau 5α-reductase los tsim DHT hauv prostate.
Cov tshuaj ua haujlwm ntawm andarine qhia txog qhov muaj peev xwm zoo ntawm andarine hauv kev txhim kho ntawm cov chaw kho mob SARMs, uas muaj cov txiaj ntsig zoo ntawm lawv cov steroidal counterparts thiab lub sijhawm zoo siab los tswj cov teebmeem androgen hauv ntau lub hom phiaj cov ntaub so ntswg, yog li txo qis kev cuam tshuam rau ib txwm muaj. .Yog li, andarine tau cog lus rau hauv kev sim tshuaj kho mob siab heev uas lub hom phiaj los kho cov hnub nyoog ntsig txog mob ntshav qab zib thiab tiv thaiv cov tsos mob ntawm cov kab mob hnyav xws li sarcopenia thiab mob qog noj ntshav cachexia.
Andarine yog ib qho kev xaiv nonsteroidal androgen receptor (AR) agonist nrog Ki ntawm 4 nM.Andarine nthuav tawm muaj zog thiab muaj txiaj ntsig zoo rau kev ua haujlwm anabolic thiab ua rau muaj kev txhawb nqa ntawm kev loj hlob hauv prostate, seminal vesicles, feem.Andarine muaj peev xwm tiv thaiv osteoporotic.
Andarine (yav tas los hu ua GTx-007; S-4; GTx007; S4) yog ib qho kev hais lus bioactive thiab xaiv tsis-steroidal androgen receptor (AR) agonist, tshwj xeeb yog xaiv androgen receptor modulator (SARM), uas muaj peev xwm muaj txiaj ntsig zoo hauv cov leeg nqaij. thiab osteoporosis.Nws qhib AR nrog Ki ntawm 4 nM thiab yog cov ntaub so ntswg xaiv rau cov kabmob anabolic.Andarine tau raug tshawb xyuas rau kev kho mob xws li cov nqaij ntshiv, pob txha pob txha thiab benign prostatic hypertrophy.Hauv cov qauv tsiaj ntawm benign prostatic hypertrophy, andarine tau pom tias txo qhov hnyav ntawm prostate nrog cov txiaj ntsig zoo sib xws rau finasteride, tab sis tsis muaj kev txo qis hauv cov leeg nqaij lossis cov tshuaj tiv thaiv androgenic.
Specifications
hom npe | SARM S4 | English npe | Andarine |
CAS nr | 401900-40-1 | molecular hnyav | 441.358 ib |
ceev | 1.5 ± 0.1g / cm3 | kub point | 698.7 ± 55.0 ° C ntawm 760 mmHg |
molecular formula | C 19 H 18 F 3 N 3 O 6 | melting point | 70-74 ºC |
PSA | 133.4800 Nws | Flash point | 376.4 ± 31.5 ° C |
LogP | 4.01 Nws | vapor siab | 0.0 ± 2.3 mmHg ntawm 25 ° C |