Tuam Tshoj muab Lidocaine CAS 137-58-6 nrog tus nqi zoo tshaj
Cov ntaub ntawv yooj yim
Soluble hauv ethanol, ether, benzene, chloroform thiab roj, insoluble hauv dej.Feem ntau siv hauv paus hydrochloride, lidocaine hydrochloride (C14H22N2O·HCL, [73-78-9]) yog cov hmoov dawb crystalline.Lub melting point yog 127-129 ℃, thiab lub melting point ntawm monohydrate yog 77-78 ℃.Soluble hauv dej, 0.5% aqueous pHO4.0-5.5.Tsis muaj ntxhiab tsw, iab hemp saj.
Kev siv
Cov khoom yog ib qho amide hauv zos anesthetic.Nws yog dav siv nyob rau hauv tshuaj loog nto, infiltration anesthesia, conduction anesthesia thiab epidural anesthesia.LD50 ntawm lidocaine hydrochloride yog 290mg / kg.
Cov ntawv thov kev kho mob muaj xws li infiltration anesthesia, epidURAL anesthesia, tshuaj loog tshuaj loog (xws li tshuaj loog mucosal thaum lub sij hawm thoracoscopy lossis phais plab), thiab cov hlab ntsha.Epinephrine tuaj yeem muab ntxiv rau cov tshuaj loog kom ntev lub sijhawm tshuaj loog thiab txo cov kev mob tshwm sim xws li lom los ntawm lidocaine.
Lidocaine kuj tseem siv tau los kho ventricular arrhythmias tom qab mob myocardial infarction, suav nrog kev ua haujlwm ntxov ntxov, ventricular tachycardia, ventricular arrhythmias tshwm sim los ntawm digitalis lom, phais mob plawv thiab mob plawv catheterization, suav nrog ventricular premature contractions, ventricular fibrillation.Nws kuj tseem siv tau rau cov neeg mob uas muaj xwm txheej epilepticus uas tsis teb rau lwm cov tshuaj tiv thaiv kab mob thiab rau cov tshuaj loog hauv zos lossis intraspinal.Nws feem ntau tsis zoo tiv thaiv supraventricular arrhythmias.
Specifications
| Khoom npe | Lidocaine |
| CAS | 137-58-6 : kuv |
| MF | C14H22N2O |
| MW | 234.34 Nws |
| EINECS | 205-302-8 ib |
| Melting point | 66-69 ° C |
| Boiling point | bp4 180-182°;bp2 159-160° ib |
| ceev | 0.9944 (zeeg) |
| Refractive Index | 1.5110 (kwv yees) |
| Fp | 9 ℃ |
| cia temp. | Khw hauv RT |
| solubility | ethanol: 4 mg/ml |
| pka ua | pKa 7.88 (H2O) (kwv yees) |
| daim ntawv | hmoov |
| xim | Dawb rau me ntsis daj |
| Dej Solubility | xyaum insoluble |
| Merck | 14,5482 ib |
| Kev ruaj ntseg: | ruaj khov.Incompatible nrog muaj zog oxidizing neeg sawv cev. |
| InChIKey | NNJVILVZKWQKPM-UHFFFAOYSA-N |
| CAS DataBase Reference | 137-58-6 (CAS DataBase Reference) |