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Prostaglandins Tshuaj 99% purity API Khoom Lumigan Bimatoprost CAS 155206-00-1 rau kho qhov muag

piav qhia luv luv:


  • Ceev:1.1 ± 0.1g / cm3
  • Boiling point:629.8 ± 55.0 ° C AT 760 mmHg
  • Melting point:66-68 ° C
  • Molecular:C25H37NO4
  • Molecular Luj:415.566 ib
  • Flash point:334.7 ± 31.5 ° C
  • Qhov Zoo Zoo:415.272247 ib
  • PSA:89.790 00 Nws
  • Logp:1.98 ib
  • Qhov tsos:Crystal khoom, hmoov
  • Chav siab:0.0 ± 1.9 mmHg AT 25 ° C
  • Refractive Index:1.591 ib
  • Product Detail

    Khoom cim npe

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    Email:ceo66@hbainuodi.com

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    Kev siv

    Bimatoprost yog ib qho tshuaj prostaglandin uas yog thawj zaug siv los kho qhov muag kab mob xws li glaucoma.Lub npe tshuaj yog Lumigan.Txawm li cas los xij, thaum lub sijhawm kho mob, tus neeg mob tau npaj txhij pom tias txoj kab uas hla, qhov ntev thiab qhov ceev ntawm nws cov plaub muag tau nce ntau.Tom qab ntawd, bimatoprost tau siv rau hauv kev sim tshuaj rau cov plaub muag zoo nkauj.Nws cov txiaj ntsig zoo ntawm cov plaub muag thickening ncaj qha coj mus rau Lattise los ntawm Lumegen lub tuam txhab tsim khoom, Allergan.Cov tshuaj tau pib thaum Lub Kaum Ob Hlis 2008. Pom zoo los ntawm US FDA, nws tau dhau los ua cov khoom lag luam rau blackening thiab thickening plaub muag.

    Thaum Lub Xya Hli 2006, bimatoprost-timolol maleate compound eye drops tsim los ntawm Tebchaws Meskas Allergan Co., Ltd. tau pom zoo los ntawm EU kws tshuaj los txo cov lus teb rau ib leeg-siv β-receptor blockers lossis prostaglandins.Intraocular siab los yog ocular hypertension nyob rau hauv cov neeg mob uas qhib-angle glaucoma uas tsis teb txaus rau analog therapy.Cov tshuaj tiv thaiv qhov muag muaj 0.0Chemicalbook3% bimatoprost thiab 0.5% timolol maleate, ib hnub ib zaug, nws tuaj yeem muab kev kho mob zoo heev hauv kev tswj lub siab, thiab cov nyhuv zoo dua li ntawm bimatoprost ib leeg.Matoprost los yog timolol txiv neej.Cov kev sim tshuaj tau lees paub tias cov tshuaj muaj qhov ua tau zoo heev, suav nrog 40% txo qhov tshwm sim ntawm ocular hyperemia piv nrog bimatoprost ib leeg.
    Rau kev kho mob glaucoma, nws kuj tseem siv tau rau hauv cov plaub muag kev loj hlob kua, qhov concentration yog 0.03%.

    Bimatoprost CAS 155206-00-1

    Specifications

    Khoom npe Bimatoprost
    CAS 155206-00-1
    Qhov ntom 1.1 ± 0.1g / cm3
    Boiling point 629.8 ± 55.0 ° C AT 760 mmHg
    Melting point 66-68 ° C
    Molecular C25H37NO4
    Molecular hnyav 415.566 ib
    Flash point 334.7 ± 31.5 ° C
    Qhov Zoo Zoo 415.272247 ib
    PSA 89.790 00 Nws
    Logp 1.98 ib
    Qhov tshwm sim Crystal Khoom
    Chav siab 0.0 ± 1.9 mmHg AT 25 ° C
    Refractive Index 1.591 ib
    Cia tej yam kev mob 20 ° C

    Qee qhov Bimatoprost CAS 155206-00-1 Kev Tshawb Fawb:

    Olaparib tau zoo tiv thaiv Brca1; p53 lub mis qog (50mg / kg intraperitoneal txhaj ib hnub), tab sis tsis muaj kev cuam tshuam rau HR-tsis muaj Ecad; p53 mis qog.Olaparib tsis muaj kev txwv tshuaj toxicity hauv cov nas uas muaj qog nqaij hlav.Olaparib tau siv los kho cov qog nqaij hlav nrog BRCA kev hloov pauv, xws li mob qog noj ntshav zes qe menyuam, mob qog noj ntshav mis, thiab mob qog noj ntshav prostate.Tsis tas li ntawd, Olaparib inhibited ATM-tsis muaj cov qog hlwb xaiv, qhia tias Olaparib tuaj yeem siv los ua tus neeg sawv cev rau kev kho mob ntawm ATM-mutated lymphoid qog.
    Olaparib yog PARP inhibitor uas tseem ua rau BRCA1 lossis BRCA2 kev hloov pauv.Olaparib muaj me ntsis cuam tshuam rau tanky (polymer) enzyme-1, thiab IC50 tus nqi ntau dua li ntawd.Olaparib ntawm qhov concentration ntawm 30-100nM ua rau SW620 hlwb kom inactivate PARP-1.BRCA1-deficient cell kab (MDA-MB-463[1] thiab HCC1937) yog hypersensitive rau Olaparib piv rau BRCA1- thiab BRCA2-tso xovtooj ntawm tes (Hs578T, MDA-MB-23, T47D) Olaparib inhibits PARP thiab blocks base excision Repair , ua rau muaj zog rhiab heev ntawm KB2P hlwb rau Olaparib.Qhov tshwm sim yog hloov dua siab tshiab ntawm ib leeg-strand so rau ob-strand so thaum lub sij hawm DNA replication, li no activating BRCA2-dependent recombination txoj kev.
    Bimatoprost yog ib tug hluavtaws prostamide F2α derivative, uas muaj peev xwm xaiv simulate cov nyhuv ntawm prostamine tsim nyob rau hauv lub cev, nce tus nqi ntawm aqueous lom zem ntau lawm, txo qhov tsis kam ntawm aqueous lom zem outflow, thiab ua rau kom lub trabecular network channel thiab uveal sclera Nws yog xam tau tias yog rau aqueous lom zem ntau lawm. yog cov tshuaj tiv thaiv kab mob glaucoma hauv zos nrog cov txiaj ntsig zoo tshaj plaws ntawm kev txo qis intraocular siab.Nws yog qhov tsim nyog rau kev kho mob ntawm qhov qhib-angle glaucoma (POAG) lossis qhov muag siab uas tsis muaj txiaj ntsig nrog rau lwm cov tshuaj intraocular siab-txo qis.Cov neeg mob ntshav siab (OHT).

    Sau tseg:

    Yog tias koj txaus siab rau, thov hu rau peb dawb, peb yuav teb rau lub sijhawm.Vam tias peb muaj kev koom tes.


    Sau koj cov lus ntawm no thiab xa tuaj rau peb