Anti-aging Hexapeptide-11 CAS 161258-30-6 Txo cov tsos ntawm wrinkles
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Hom npe | Hexapeptide-11 | English npe | Hexapeptide-11 |
---|---|---|---|
CAS nr | 161258-30-6 |
Cov mis mos molecular | C36H48N6O7 |
---|---|
Molecular hnyav | 676.80200 ib |
Qhov tseeb loj | 676.35800 ib |
PSA | 201.71.000 Nws |
LogP | 4.09300 Nws |
Kev siv:
Hexapeptide-11 yog ib qho tshiab modulator ntawm proteostasis network hauv tib neeg diploid fibroblasts.
Hexapeptide-11 txo cov tsos ntawm cov kab zoo thiab wrinkles, ua qhov no zoo heev ntxiv rau txhua yam kev tu tawv nqaij thiab cov khoom tiv thaiv kev laus.Nws muaj cov txheej txheem tshwj xeeb ntawm cov amino acids uas pab tswj cov qib collagen thiab txhawb nqa elasticity ntawm daim tawv nqaij.
Kev nthuav tawm ntawm fibroblasts rau Hexapeptide-11 txhawb nqa koob tshuaj thiab lub sijhawm ua haujlwm ntawm proteasome, autophagy, chaperones thiab cov lus teb antioxidant ntsig txog cov noob.Tsis tas li ntawd, nws tau txhawb nqa kev sib sau ua ke nuclear ntawm Nrf2;Kev nthuav qhia ntau dua ntawm cov protein proteasomal subunits thiab nce proteasome peptidase kev ua ub no.Nyob rau hauv txoj kab nrog cov kev tshawb pom no peb tau sau tseg tias Hexapeptide-11 tau muab kev tiv thaiv tseem ceeb hauv fibroblasts tiv thaiv oxidative-stress-mediated premature cellular senescence, thaum nyob rau hauv vivo daim tawv nqaij deformation soj ntsuam nyob rau hauv tib neeg kev kawm nws txhim kho daim tawv nqaij elasticity.