Nimetazepam CAS: 2011-67-8 hypnotic tranquilizer

ʻO Nimetazepam kahi mea hana hypnotic, kahi derivative benzodiazepine.Ua hana mua ia i ka makahiki 1964 e kahi hui o Hoffmann-La Roche.Loaʻa iā ia ka hypnotic ikaika, anti-anxiety, hoʻomaha a me nā hopena hoʻomaha hoʻomaha ʻiʻo.ʻO ka Nimetazepam kahi anticonvulsant maikaʻi loa.Kūʻai ʻia ʻo ia ma ke ʻano he 5-miligram papa i kapa ʻia ʻo Erimin, kahi inoa inoa i hana ʻia a kūʻai ʻia e Sumitomo, kahi hui Iapana nui.ʻO Iapana wale nō ka ʻāina ma ka honua e hana i ka nimetazepam.Ma waho o Iapana, loaʻa ʻo Erimin ma ka hapa nui o ka Hikina a me ka Hikina Hema o Asia a hoʻohana nui ʻia ma ke ʻano he lāʻau lapaʻau pōkole no ka poʻe me ka insomnia koʻikoʻi i paʻakikī i ka hiamoe a i ʻole ka hiamoe.Ua ho'ōki ʻo Sumitomo i ka hana ʻana iā Erimin mai Nowemapa 2015. Aia nō ia ma ke ʻano he generic a i ʻole Lavol.

Ua kuhikuhi nui ʻia ʻo Nimetazepam i nā makahiki 1980 a me 1990, ʻoiai ma Iapana, Malaysia, Brunei, Philippines, Thailand, Indonesia, Hong Kong a me Singapore.Me ka hoʻomāinoino a me ka addiction rampant, ua hāʻule nui nā ʻōlelo kuhikuhi no ka lāʻau mai ka makahiki 2005. Hoʻohana nui ʻia ʻo ia ma ke ʻano he anticonvulsant i nā keiki.Hoʻohana ʻia nō hoʻi ia i nā hihia koʻikoʻi a hoʻonāwaliwali o ka insomnia ma nā ʻōnaehana inpatient a i ʻole ka mālama maʻi outpatient no ka wā pōkole.No kēia kumu, ua hoʻohana pinepine ʻia nā lāʻau hiamoe benzodiazepines Esazolam a me nitrazepam ma mua o ka nitrazepam.ʻO nā antidepressants e like me trazodone a me mirtazapine a i ʻole Zopiclone a me zolpidem nā lāʻau lapaʻau mua no ka insomnia.

ʻOiai ua emi iho ka lāʻau o ka nimetazepam, ʻoi aku ka nui o ka hoʻohana ʻana i ka lāʻau lapaʻau ma Brunei, Singapore, Malaysia a me Philippines.Hoʻohana maʻamau ia me ka methamphetamine a me ka ecstasy, a me nā opioids (ʻoi aku ka heroin a me ka morphine).Aia ʻo Nimetazepam i nā palena kānāwai koʻikoʻi ma Malaysia, kahi i liʻiliʻi ai ka lāʻau lapaʻau, akā he nui nā lāʻau i kūʻai ʻia ma ka mākeke ʻeleʻele ma lalo o ka inoa ʻo Nimetazepam.ʻO ka diazepam a me ka nitrazepam kekahi o nā benzodiazepines maʻamau i hoʻohana ʻia ma ka ʻāina, a no laila, hoʻohuli pinepine ʻia lākou a kūʻai ʻia ma ka mākeke ʻeleʻele, e like me ka nitrazepam.

ʻO ka hana hewa ʻole o Nimezepam (kūʻai ʻia e like me Erimin-5) ua pālahalaha ʻia ma ka ʻāina.Ua hoʻomau ka hoʻohana ʻana i ka nimetazepam i nā makahiki 2010.ʻO ka hopu ʻana i nā papa Erimin-5 i hana hewa ʻole ʻia i hui pū ʻia me ka hopu ʻana i ka methamphetamine ma Malaysia.Ua hoʻāʻo ʻia kahi helu liʻiliʻi o 46 mau papa Erimin-5 i hoʻopaʻa ʻole ʻia no ko lākou mau waiwai kino a me nā mea kemika.ʻO ka mea hoʻoikaika ikaika, dopant, diluent mua, a me ka dye ke ʻano kemika o ka papa.Ua hōʻike ʻia nā hopena ʻo Nimetazepam ka mea hana maʻamau i ka hapa nui o nā papa i hopu ʻia.Ua ʻike ʻia ʻo Lactose ka mea hoʻoheheʻe nui i ka hapa nui o nā laʻana, a ukali ʻia e ka mannitol a laila dicalcium phosphate dihydrate.Loaʻa ka melemele ka napoʻo ʻana o ka lā i ka nui o nā laʻana pila, hoʻohana wale ʻia a i hui pū ʻia me nā kala ʻē aʻe (e laʻa me ka tartar a me Lichenol 4R) e hāʻawi i ka pila i kahi kala peach/alani.Aia i loko o nā papa ʻōmaʻomaʻo i loko o ka laʻana nā ʻulaʻula uliuli a me ka wai tartar.ʻO ka Diazepam kahi lāʻau anti-anxiety a ʻo ia ka mea hana i hoʻokahi wale nō o nā papa 46.Ua ʻike ʻia ʻo Nitrazepam, kahi mea hoʻomaha hoʻomaha a me ka hypnotic a me ka lāʻau makua o ka nitrazepam, he hui lua, me ka caffeine ka mea nui i hui ʻia i ʻekolu papa.

I ka makahiki 2003, ua hopu ʻo Singapore i 94,200 mau papa Erimin-5.Ua hoʻāʻo ʻia ka ʻoihana o ka Central Narcotics Board (CNB) i nā papa a ua hōʻoia nā hopena he nitrazepam maoli lākou.