Larazotide acetate CAS 881851-50-9
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ʻano:
inoa maʻamau | Larazotide Acetate | inoa Pelekane | Larazotide acetate |
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Helu CAS | 881851-50-9 | kaumaha molekala | 785.88500 |
molecular formula | C34H59N9O12 |
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nuipa pololei | 785.42800 |
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PSA | 360.55000 |
LogP | 3.73650 |
Hoʻohana:
ʻO Larazotide acetate kahi lāʻau hoʻoponopono hoʻoponopono i loko o ka ʻōpū, i ʻike mua ʻia ʻo Innovate Biopharmaceuticals ma mua o ka hui ʻana, e hoʻāʻo ʻia nei i nā poʻe maʻi maʻi me ka maʻi celiac i kahi hoʻokolohua hoʻāʻo III.Loaʻa kēia peptide kaulahao hoʻokahi mai ka zonulin kanaka, kahi modulator i ʻike ʻia o ka permeability junction paʻa i hoʻokiʻekiʻe i ka hōʻike ʻana o ka ʻiʻo ʻōpū i nā maʻi me ka maʻi celiac.Hāʻawi pū ʻo LA i nā ʻano like like me ka Vibrio cholerae zonula occludens toxin (Zot), he enterotoxin e hoʻopau i ka hoʻopili paʻa intercellular ma o ka actin polymerization a me nā hoʻololi cytoskeletal e hoʻonui ai i ka permeability o ka ʻōpū ma o ka hōʻailona intracellular.ʻOiai ua hōʻike ʻo LA i ka ʻōlelo hoʻohiki i nā hoʻokolohua lapaʻau no nā maʻi me ka maʻi celiac, nā noiʻi hou e hoʻohana ana i nā ʻano hōʻeha holoholona like ʻole e hōʻike ana i kahi hoʻohana kūpono no LA no nā maʻi ʻē aʻe ma muli o kona hiki ke hoʻoponopono i nā hui paʻa.Ke manaʻo nei kēia mini-review e hāʻawi i kahi kumu kikoʻī o ka ʻike o kēia manawa e pili ana i kēia octapeptide.