API no ka hoʻomaʻemaʻe kiʻekiʻe ʻo Pharma CAS14769-73-4 Hydrochloride Levamisole Base
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ʻIke Kumu
Wehewehe
He 6-phenyl-2,3,5,6-tetrahydroimidazo [2,1-b] [1,3] thiazole i loaʻa ka hoʻonohonoho S.Hoʻohana ʻia (ma ke ʻano he paʻakai monohydrochloride) no ka mālama ʻana i nā maʻi ilo parasitic i loko o nā puaʻa, hipa a me nā pipi a ua hoʻohana mua ʻia i loko o nā huma ma ke ʻano he adjuvant no ka chemotherapy no ka mālama ʻana i nā maʻi maʻi like ʻole.Hoʻohana nui ʻia ʻo ia ma ke ʻano he mea moekolohe i ka coccaine.
Nā hōʻailona
ʻO Levamisole (Ergamisol) kahi lāʻau antiparasitic i ʻike ʻia e hoʻomaikaʻi i ka hana T-cell a me ka pale kino.Hoʻomaikaʻi ka lāʻau lapaʻau i ke ola o nā maʻi me nā maʻi maʻi colorectal resected ke hui pū ʻia me 5-fluorouracil;ʻaʻole ʻike ʻia ke ʻano o kēia pilina.ʻAʻohe hana antitumor o Levamisole e kūʻē i ka maʻi maʻi maʻi i hoʻokumu ʻia a i ʻole metastatic a ʻaʻole i ʻike ʻia he pono i ka adjuvant therapy o nā maʻi maʻi maʻi ʻē aʻe ma mua o ka maʻi kanesa colorectal.
ʻO nā hopena koʻikoʻi nui o levamisole he nausea a me ka anorexia.Ua ʻike ʻia ka ʻili ʻili, ka ʻuʻu, nā hōʻailona like me ka flu, a me ke kuni.
Nā hōʻailona
Ua hoʻokumu mua ʻia ʻo Levamisole (Ergamisol) ma ke ʻano he lāʻau antihelminthic.Hoʻoikaika ia i nā hopena stimulatory o nā antigens, mitogens, lymphokines, a me nā mea chemotactic ma nā lymphocytes, granulocytes, a me nā macrophages.Ua hōʻike ʻia e hoʻonui i ka pale ʻana o ka cell T cell-mediated immunity.
Ua hoʻohana maikaʻi ʻia ʻo Levamisole i ka mālama ʻana i nā maʻi maʻi.Ua ʻae ʻia no ka hoʻohana pū ʻana me ka fluorouracil i ka mālama ʻana i ka maʻi maʻi colorectal.
Hoʻohana
Hoʻohana Mea hoʻololi pane olaola.
Hoʻohana Hoʻohana ʻia ʻo Levamisole no nā maʻi immunodeficient mua a me ka lua, nā maʻi autoimmune, nā maʻi maʻi a me nā maʻi hou, adenocarcinoma ʻōpū nui, helmintosis, a me ka rheumatoid arthritis.ʻO nā inoa like o kēia lāʻau lapaʻau he decaris, tetramizole, a me nā mea ʻē aʻe.
ʻO Levimasole kekahi lāʻau koho no ka ascardiasis.Hōʻike ka nui o nā noiʻi e hoʻōla hoʻokahi dosis o levamisole mai 90 a 100% o nā maʻi me ka ascardiasis, ʻoi aku ka poʻe i loaʻa i ka maʻi A. duodenale.ʻAʻole maikaʻi loa ia i ka ancylostomiasis a me ka strongyloidiasis.Akā naʻe, ʻaʻole kūpono ia e kūʻē iā N. americanus.Me he mea lā he hopena gangliostimulating ma nā ʻiʻo parasite ma nā ʻāpana parasympathetic a me nā ʻāpana aloha.Eia kekahi, ua manaʻo ʻia he hopena immunomodulatory kēia lāʻau i ka mea hoʻokipa.ʻO nā inoa like o kēia lāʻau lapaʻau he decaris, solacil, ergamisol, tramisol, immunol, a me nā mea ʻē aʻe.
Hoʻohana lāʻau lapaʻau
Ascariasis Hookworm ma'i
Ua hoʻohana ʻia ʻo Levamisole i ka maʻi rheumatoid a me kekahi mau kūlana ʻē aʻe i ʻōlelo ʻia e pane i kāna hana immunomodulatory.
Hana Lapaau
Antiinflammatory
Hana antimicrobial
ʻO kāna hana nui ke kū'ē iā Asc.nā lumbricoides a me nā ʻīlio makau.Paʻa nā ilo a hele aku i loko o ka feces i loko o kekahi mau hola.
Na Laau Laau Laau
ʻO ka l-isomer o ka tetramisole, loaʻa e like me ka monohydrochloride.ʻAʻohe hana anthelmintic ka d-isomer.Hiki ke hoʻoheheʻe ʻia i ka wai a paʻa i ka maloʻo.
Mechanism o ka hana
He hana immunomodulating ka Levamisole.Ua manaʻoʻiʻo ia e hoʻoponopono i nā mīkini kelepona o ka ʻōnaehana pale, a pili paha ke ʻano o kāna hana me ka hoʻoulu ʻana a me ka ulu ʻana o ka T-lymphocytes, ka nui o nā monocytes a me ka hoʻoulu ʻana o nā macrophages, a me ka hoʻonui ʻana i ka hana a me ka hemotaxis o neutrophylic. granulocytes.Hōʻike pū ʻo Levamisole i ka hana anthelmint.Hoʻonui ia i ka resistivity holoʻokoʻa o ke kino a hoʻihoʻi hou i ka T-lymphocyte a me ka hana phagocyte.Hiki iā ia ke hoʻokō i kahi hana immunomodulatory ma o ka hoʻoikaika ʻana i ka hopena nāwaliwali o ka pale ʻana o ke kelepona, hoʻonāwaliwali i ka hopena ikaika, a ʻaʻohe hopena i ka hopena maʻamau.