GW-0742 SARMs Pauda |GW610742 CAS 317318-84-6
Hoʻohana
No ka momona, ka maʻi diabetes, dyslipidemia a me ka maʻi maʻi cardiovascular He lāʻau hoʻokolohua i manaʻo ʻia e kāohi i nā lipids a hoʻonui i ke kiʻekiʻe o ka HDL, a i ʻole ka cholesterol maikaʻi, i ke kahe koko.ʻO kahi pūnaewele-permeable, thiazolyl pūhui e hana like me ka potent, affinity kiʻekiʻe, PPARδ agonist.Hōʻike i ka koho no PPARδ i hoʻohālikelike ʻia me PPARα a me PPARγ.ʻAʻole ia e hoʻokuʻu i kekahi hana e kūʻē i nā mea hoʻokipa nuklea a i ʻole nuklea.Hōʻike ʻia e hoʻonui i ka cholesterol efflux a me ka hōʻike ABAC1 i nā macrophages, fibroblasts, a me nā ʻōpū ʻōpū.
Hoʻohana ʻia ʻo Cardarine e nā mea pāʻani e hoʻokūkū ana i nā haʻuki like ʻole.No ka laʻana, hiki i ka poʻe haʻuki hoʻomanawanui ke hoʻonui i ka hoʻoikaika kino ma ka hoʻopaʻa ʻana i kēia PPAR me ka AMP analog drug AICAR, a i ʻole holo cardarine solo.ʻO ka hopena, e loaʻa iā lākou ka hiki ke piʻi i nā RPM kiʻekiʻe i ka wā o kā lākou holo ʻana me ka ʻole o ka paʻi ʻana i ka nui o ka puʻuwai puʻuwai.ʻO kēia ka mea e ʻae ai i ka mea kukini/kaikikala/ʻauʻau kai e hoʻopunipuni i ko lākou mau puʻuwai kiʻekiʻe loa a hele lōʻihi me ka ʻole o ka makani, e hoʻolilo i kēia waihona i mea kaua kupaianaha e hoʻohana ai i nā haʻuki hoʻomanawanui.ʻOiaʻiʻo, mai ka ʻike pilikino hiki iaʻu ke haʻi aku hiki i ka cardarine ke kīkēkē ma luna o 30-45 kekona mai kahi manawa 5K inā hoʻohana ʻia e alakaʻi i kahi heihei.
wehewehe
KEY WORDS: ʻO ka lilo ʻana o ka momona, hoʻomaikaʻi i ka hoʻomanawanui, ʻaʻohe hopena ʻaoʻao, bodybuilder, lāʻau no ka momona a kōkua i ka mālama ʻana i ka lean mass, hoʻonui i ka nui o ka ʻiʻo.
Hoʻopiliʻiaʻo Cardarine (GW-501516) i ka māhele o SARMS, akā naʻe ma keʻano a me ka weheweheʻana, he modulator PPAR.Ma ke ʻano he modulator PPAR, hoʻāla ia i ka kinase protein AMP-activated a hoʻoulu i ka lawe ʻana o ka glucose i ka ʻiʻo ʻiʻo iwi.Loaʻa iā GW-501516 nā mana e hoʻohuli i nā pilikia metabolism ma o ka hoʻoulu ʻana i ka hoʻokahe ʻana i ka momona momona.Manaʻo ʻia he lāʻau lapaʻau ikaika no ka momona a me nā kūlana pili ʻē aʻe.
ʻO GW501516 ka inoa o kahi lāʻau lapaʻau Glaxo Wellcome (ʻo ka GW ke kū nei no ka hui a ʻo ka helu ka mea o ka huahana).Ua ʻike ʻia ʻo GW-501,516, GW1516, GSK-516).ʻO ia kahi agonist receptor PPARδ ʻaʻole i lawe ʻia ma mua o nā hoʻokolohua lapaʻau.No laila ua pāpā ʻia i ka haʻuki.Ua kūpono ia ma nā wahi he nui ma ka papa inoa, e like me "he peroxisome Proliferator Activated Receptor δ (PPARδ) agonists (eg GW501516)".Akā, aia nō ia ma lalo o ka WADA hopu hou a pau "nā mea i ʻae ʻole ʻia" pauku e manaʻo nei e hoʻōki i ka lāʻau laikini ʻole i hoʻohana ʻia e nā mea pāʻani.
ʻO GW501516 (ʻike pū ʻia ʻo GW-501,516, GW1516, GSK-516) he agonist PPAR& receptor i hana ʻia ma ka hui pū ʻana ma waena o Ligand Pharmaceuticals a me GlaxoSmithKline i nā makahiki 1990, ua hoʻokomo ʻia i loko o ka hoʻomohala ʻana i ka lāʻau lapaʻau no nā maʻi metabolic a me nā maʻi cardiovascular. , a ua haʻalele ʻia i ka makahiki 2007 no ka mea ua hōʻike ʻia ka hoʻāʻo ʻana i nā holoholona i ka lāʻau lapaʻau e ulu wikiwiki ai ka maʻi kanesa i loko o kekahi mau kino.
I ka makahiki 2007, ua paʻi ʻia ka noiʻi e hōʻike ana i ka hoʻonui nui ʻana o nā kiʻekiʻe o GW501516 i nā ʻiole i kā lākou hana kino;Ua kūkākūkā nui ʻia ka hana ma nā pāpaho kaulana, a ua alakaʻi ʻia i kahi mākeke ʻeleʻele no ka moho lāʻau lapaʻau a me kāna hana hoʻomāinoino ʻia e nā mea pāʻani ma ke ʻano he doping agent.
Nā noi
Hiki ke hoʻohana ʻia ʻo GW501516 e nā mea pāʻani ma ke ʻano he lāʻau ergogenic hoʻonui i ka hana ʻaʻole i mālama ʻia e nā lula a ʻike ʻia e nā hoʻokolohua maʻamau.ʻO kekahi o nā mea noiʻi nui mai ke aʻo ʻana e pili ana i ka hoʻoikaika ʻana i ka hoʻomanawanui i hoʻomohala i kahi hoʻāʻo mimi e ʻike ai i ka lāʻau lapaʻau, a ua loaʻa iā ia i ke Kōmike Olumepika International.
Hoʻoulu ʻo GW i ka lawe ʻana i ka glucose a me ka ʻiʻo ʻiʻo iwi.Hoʻopau ʻo ia i ka momona ma o ka hoʻoulu ʻana i ka momona momona.Manaʻo ʻia he lāʻau lapaʻau no ka momona ma muli o kona hiki ke hoʻoheheʻe wikiwiki i ka momona.Eia kekahi, ʻōlelo ʻia ʻo Cardarine e hoʻonui i ka HDL ma ka awelika o 79% (kolesterol maikaʻi) a hoʻemi i ka LDL (kolesterol maikaʻi ʻole) i nā hoʻokolohua Phase II o kēia manawa.ʻO GW 501516 kahi agonist PPARδ.Kōkua kēia i ka hoʻonui ʻana i kāu mau pae HDL mai kahi hōʻike i hoʻonui ʻia o ka mea lawe cholesterol ABCA1.
Hoʻoulu ʻo GW i ka lawe ʻana i ka glucose a me ka ʻiʻo ʻiʻo iwi.Hoʻopau ʻo ia i ka momona ma o ka hoʻoulu ʻana i ka momona momona.Manaʻo ʻia he lāʻau lapaʻau no ka momona ma muli o kona hiki ke hoʻoheheʻe wikiwiki i ka momona.Eia kekahi, ʻōlelo ʻia ʻo Cardarine e hoʻonui i ka HDL ma ka awelika o 79% (kolesterol maikaʻi) a hoʻemi i ka LDL (kolesterol maikaʻi ʻole) i nā hoʻokolohua Phase II o kēia manawa.ʻO GW 501516 kahi agonist PPARδ.Kōkua kēia i ka hoʻonui ʻana i kāu mau pae HDL mai kahi hōʻike i hoʻonui ʻia o ka mea lawe cholesterol ABCA1.
Puke a me ka lawe ʻana
