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GHRP-2/Pralmorelin CAS:158861-67-7 d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide

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  • NO KA CAS:170851-70-4
  • inoa:GHRP-2/Pralmorelin
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    Hoʻohana

    Pralmorelin (INN) (inoa kālepa GHRP Kaken 100; Nā inoa code hoʻomohala mua KP-102, GPA-748, WAY-GPA-748), i ʻike ʻia ʻo pralmorelin hydrochloride (JAN) a me pralmorelin dihydrochloride (USAN), a ʻo ia hoʻi, Growth ʻO ka hormone e hoʻokuʻu ana i ka Peptide 2 (GHRP-2), kahi mea huna hormone ulu (GHS), ua hoʻohana ʻia ma ke ʻano he mea hōʻike diagnostic a kūʻai ʻia ma ka palapala hoʻohālikelike hoʻokahi-dose e Kaken Pharmaceutical o Iapana no ka loiloi ʻana i ka hemahema o ka hormone ulu (GHD).

    ʻO Pralmorelin kahi lāʻau peptide synthetic me ka hana waha.ʻO ke kikoʻī, he analogue ia o ka methoxyenkephalin me ke kaʻina amino acid D-Ala-D -(β-naphthyl) -ala-trp-d-phe -Lys-NH 2. Hana ia ma ke ʻano he auxin e hoʻokuʻu ana i ka peptide/growth hormone secretin receptor ( GHSR) agonist a ʻo ia ka lāʻau lapaʻau mua o kona ʻano e hoʻokomo ʻia i loko o ke keʻena.ʻO ka hoʻohana ʻana i ka lāʻau lapaʻau e hoʻonui nui i ka pae plasma growth hormone (GH) a hilinaʻi i ka pōloli a hoʻonui i ka ʻai i nā kānaka.

    Ke aʻo ʻia nei ʻo Pralmorelin no ka GHD a me ke kiʻekiʻe pōkole (pituitary dwarfism) a komo i nā hoʻokolohua lapaʻau ma ka pae II no kēia mau hōʻailona, ​​​​akā ʻaʻole i hiki i ka mākeke.ʻO kēia paha no ka mea hiki i ka pramoline ke hoʻonui i nā pae GH plasma he haʻahaʻa loa i nā maʻi GHD ma mua o nā kānaka olakino.

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