Sarm S4 Andarine Melemele pauka
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Hoʻohana
ʻO Andarine (S-4) ka hui i loaʻa ʻia ka arylpropionamide [S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide] mua wehewehe ʻia e Yin et al.e lilo i mea koho modulator receptor androgen (SARM).Ua hōʻike ʻia ʻo Andarine (S-4) e nā haʻawina in vitro a me in vivo he agonist anabolic pono, me ka ʻole o nā hopena ʻaoʻao e pili pinepine ana me nā steroid anabolic-androgenic, e pili nui ana i ka pilina substrate no 5α-reductase e hana i ka DHT i ka prostate.
Hōʻike ka hana pharmacological o andarine i ka mana nui o ka andarine i ka hoʻomohala ʻana i nā SARM i loaʻa i ka maʻi, e hāʻawi ana i nā pono therapeutic kūʻokoʻa ma luna o kā lākou mau mea steroidal a me kahi manawa hoihoi e hoʻoponopono ʻokoʻa i nā hopena androgen i nā ʻiʻo i hoʻopaʻa ʻia, no laila e hōʻemi i ka hoʻopilikia ʻana i ka maʻamau. .No laila, ua hoʻohiki ʻo andarine i nā hoʻokolohua lapaʻau holomua e manaʻo nei e mālama i nā maʻi e pili ana i ka makahiki a me ka pale ʻana i nā hōʻailona o nā maʻi koʻikoʻi e like me ka sarcopenia a me ka cachexia cancer.
ʻO Andarine kahi agonist nonsteroidal androgen receptor (AR) koho me Ki o 4 nM.Hōʻike ʻo Andarine i ka hana anabolic ikaika a maikaʻi a hopena i ka hoʻoulu ʻana i ka nui o ka ulu ʻana o ka prostate, seminal vesicle, kēlā me kēia.Loaʻa iā Andarine nā waiwai antiosteoporotic.
ʻO Andarine (ʻike mua ʻia ʻo GTx-007; S-4; GTx007; S4) he agonist agonist non-steroidal androgen receptor (AR), ʻo ia hoʻi kahi modulator receptor androgen receptor (SARM), i loaʻa ka pono i ka hoʻopau ʻana i ka ʻiʻo. a me ka osteoporosis.Hoʻola ia iā AR me kahi Ki o 4 nM a he kiko-koho no nā kino anabolic.Ke noiʻi ʻia nei ʻo Andarine no ka mālama ʻana i nā maʻi e like me ka pau ʻana o ka ʻiʻo, osteoporosis a me ka hypertrophy prostatic benign.I loko o kahi holoholona holoholona o benign prostatic hypertrophy, ua hōʻike ʻia ʻo andarine e hōʻemi i ke kaumaha prostate me ka maikaʻi like me ka finasteride, akā me ka ʻole o ka hoʻemi ʻana i ka nui o ka ʻiʻo a i ʻole nā hopena anti-androgenic.
Nā kikoʻī
inoa maʻamau | SARM S4 | inoa Pelekane | Andarine |
Helu CAS | 401900-40-1 | kaumaha molekala | 441.358 |
mānoanoa | 1.5±0.1 g/cm3 | wahi paila | 698.7±55.0 °C ma 760 mmHg |
molecular formula | C 19 H 18 F 3 N 3 O 6 | wahi hehee | 70-74ºC |
PSA | 133.48000 | Kuhikuhi uila | 376.4±31.5 °C |
LogP | 4.01 | kaomi mahu | 0.0±2.3 mmHg ma 25°C |