Tesamorelin CAS: 804475-66-9 Unii-mqg94m5eeo Th 9507
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Amfani
Tesamorelin (INN) (sunan ciniki Egrifta SV) wani nau'i ne na roba na haɓakar hormone mai sakin hormone (GHRH) don maganin lipodystrophy mai alaka da HIV kuma an amince da shi a 2010. An samar da shi kuma ya haɓaka ta Theratechnologies, Inc. Canada.Magungunan peptide na roba ne wanda ya ƙunshi dukkan amino acid 44 na GHRH na ɗan adam tare da ƙari na ƙungiyar trans-3-hexenoic acid.
Hanyar aiki
Tesamorelin wani fili ne da aka gyara N-terminus bisa jerin amino acid 44 na GHRH na ɗan adam.Wannan nau'i na roba da aka gyara ya fi tasiri da kwanciyar hankali fiye da peptides na halitta.Hakanan yana da juriya ga tsagewa ta dipeptide aminopeptidase fiye da GHRH na ɗan adam.Yana ƙarfafa haɓakar GH na endogenous da saki kuma yana haɓaka matakan haɓakar haɓakar insulin-kamar (IGF-1).GH ɗin da aka saki sannan yana ɗaure ga masu karɓa waɗanda ke kan gabobin jiki daban-daban kuma suna daidaita tsarin jiki.Wannan ƙa'ida ta fi dacewa da haɗuwa da hanyoyin anabolic da lipolysis.Koyaya, babban hanyar da aka samo tesamoline don rage yawan kitsen jiki shine rage matakan triglyceride bayan lipolysis.