Matsakaicin magunguna 99% tsabta foda CAS 86386-73-4 Fluconazol
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Bayanan asali
Fluconazole-D4 ya bayyana a matsayin fari zuwa rawaya-fari crystalline foda kuma yana da ɗan wari tare da ɗanɗano mai ɗaci.
Yana da sauƙi mai narkewa a cikin glacial acetic acid, methanol ko ethanol, da wuya mai narkewa a cikin ruwa kuma kusan ba zai iya narkewa a cikin ether tare da ma'anar narkewar zama 137 ~ 141.6 ℃, ko ma'anar narkewa shine 138 ~ 140 ℃ (wanda aka samo daga ethyl acetate-hexane).
Amfani
Wannan samfurin na fluorinated triazole maganin antifungal tare da antifungal bakan yana kama da ketoconazole amma aikin antifungal ya fi ketoconazole.
Hanyar aiwatar da shi shine ta hanyar hana mahimman abubuwan da ke cikin ƙwayar fungal cell membrane, ergosterol biosynthesis enzyme, toshe haɗin ergosterol da karya amincin bangon sel na fungal, yana ƙara hana haɓakarsu da haifuwa.
Samfurin yana da tasirin antifungal mai ƙarfi akan Candida albicans, Microsporum canis, Cryptococcus neoformans, histoplasma capsulatum da epidermophyton.
Abubuwan Sinadarai
Fluconazole-D4 fari ne zuwa Kashe-fari mai ƙarfi
Yana amfani da Labeled Fluconazole (F421000).Ana amfani dashi azaman antifungal.
Yana amfani da anticholinergic
Ana amfani da Fluconazole-D4 don maganin cututtukan fungal.
Yana amfani da A triazole m antifungal wakili.
Alamu
Fluconazole (Diflucan) na iya zama mafi kyawu kuma yana iya zama ƙasa da hepatotoxic fiye da ketoconazole, amma yana da tsada da yawa, muhimmin la'akari da aka ba da tsayin da ake buƙata don yawancin cututtukan fungal na fata.