Nimetazepam CAS: 2011-67-8 hypnotic tranquilizer

Nimetazepam matsakaicin aikin hypnotic ne, asalin benzodiazepine.An fara haɗa shi a cikin 1964 ta ƙungiyar Hoffmann-La Roche.Yana da karfi hypnotic, anti-damuwa, calming da kwarangwal tsoka shakatawa effects.Nimetazepam kuma yana da tasiri na musamman na anticonvulsant.Ana sayar da shi a matsayin kwamfutar hannu mai nauyin milligram 5 da ake kira Erimin, sunan mai suna Sumitomo, babban kamfanin Japan ya yi kuma ya sayar.Japan ita ce kasa daya tilo a duniya da ke samar da nimetazepam.A wajen Japan, Erimin yana samuwa a mafi yawan Gabas da Kudu maso Gabashin Asiya kuma ana amfani dashi a matsayin magani na ɗan gajeren lokaci ga mutanen da ke fama da rashin barci mai tsanani waɗanda ke da wuya su yi barci ko barci.Sumitomo ya daina yin Erimin tun Nuwamba 2015. Har yanzu ana samunsa azaman jigon ko Lavol.

An rubuta Nimetazepam sosai a cikin 1980s da 1990s, musamman a Japan, Malaysia, Brunei, Philippines, Thailand, Indonesia, Hong Kong da Singapore.Tare da cin zarafi da jaraba, takardun magani na miyagun ƙwayoyi sun ragu sosai tun 2005. Ana amfani da shi da farko a matsayin anticonvulsant a cikin yara.Har ila yau, ana amfani da ita a cikin mafi tsanani kuma mai raɗaɗi na rashin barci a cikin Saitunan marasa lafiya ko magani na ɗan gajeren lokaci.Don wannan dalili, an yi amfani da kwayoyin barci benzodiazepines Esazolam da nitrazepam akai-akai fiye da nitrazepam.Maganin rage damuwa irin su trazodone da mirtazapine ko Zopiclone da zolpidem sune magungunan layin farko na rashin barci.

Kodayake maganin nimetazepam ya ragu, cin zarafin miyagun ƙwayoyi ya kasance mai girma a Brunei, Singapore, Malaysia da Philippines.Ana yawan amfani da shi tare da methamphetamine da ecstasy, da kuma opioids (musamman heroin ko morphine).Nimetazepam yana fuskantar tsauraran takunkumin doka a Malaysia, wanda ya sa magungunan suka yi karanci, amma yawancin kwayoyin da ake sayarwa a kasuwar baƙar fata da sunan Nimetazepam na jabu ne.Diazepam da nitrazepam suna daga cikin benzodiazepines da aka fi amfani da su a yankin, don haka, ana karkatar da su da kuma sayar da su a kasuwar baƙar fata, galibi kamar nitrazepam.

Kera Nimezepam ba bisa ka'ida ba (wanda ake siyar da shi azaman Erimin-5) ya yadu a yankin.Cin zarafin nimetazepam ya ci gaba da karuwa a cikin 2010s.Kame na allunan Erimin-5 da aka kera ba bisa ka'ida ba sun zo daidai da kama methamphetamine a Malaysia.An gwada kananan allunan Erimin-5 guda 46 da aka kama ba bisa ka'ida ba, saboda kayansu na zahiri da na sinadarai.Abubuwan da ke aiki, dopant, diluent na farko, da rini sun ƙunshi halayen sinadarai na kwamfutar hannu.Sakamakon ya nuna cewa Nimetazepam shine sinadari mai aiki na yau da kullun a cikin mafi yawan allunan da aka kama.An gano Lactose a matsayin babban mai narkewa a yawancin samfurori, sannan mannitol ya biyo baya sannan dicalcium phosphate dihydrate.An samo launin rawaya na faɗuwar rana a yawancin samfuran kwaya, ana amfani da su kaɗai ko a haɗe tare da wasu rini (misali tartar da Lichenol 4R) don baiwa kwaya ɗin launin peach/orange.Koren allunan a cikin samfurin sun ƙunshi shuɗi mai haske da rini na tartar.Diazepam da farko maganin damuwa ne kuma shine sashi mai aiki a cikin ɗayan allunan 46 kawai.Nitrazepam, mai kwantar da hankali mai karfi da hypnotic da kuma mahaifa na miyagun ƙwayoyi na nitrazepam, an samo shi azaman fili na biyu, tare da maganin kafeyin shine babban abin da aka haɗa a cikin allunan guda uku.

A shekarar 2003, Singapore ta kwace allunan Erimin-5 guda 94,200.dakin gwaje-gwaje na Hukumar Kula da Magunguna ta Tsakiya (CNB) ta gudanar da gwaje-gwaje akan allunan kuma sakamakon ya tabbatar da cewa lallai nitrazepam ne.