Gabatarwa
Minoxidil, kuma aka sani da dogon matsa lamba idine, Minoxidil, kwayoyin dabara da kuma zumunta kwayoyin nauyi C9H15N5O = 209.25, shi ne fari ko fari crystalline foda, dan kadan mai narkewa a cikin ruwa ko chloroform, dan kadan mai narkewa a cikin ethanol, dan kadan mai narkewa a cikin acetone, mai narkewa a cikin acetic acid.Yana iya yin aiki kai tsaye akan bangon jirgin jini, dilate arterioles, rage juriya na gefe, rage hawan jini, da haɓaka bugun zuciya da fitarwar zuciya.Koyaya, tasirin antihypertensive yana da mahimmanci kuma yana dawwama fiye da hydrazine.
Pharmacological tasirin
Minoxidil yana fadada arterioles kai tsaye, don haka rage hawan jini, amma ba a san ainihin hanyar ba.Wannan samfurin baya fadada venules.Rage juriya na jijiyoyin jijiyoyin jiki yana haifar da saurin juyewar bugun zuciya da ƙara yawan fitarwar zuciya.Ayyukan renin yana ƙaruwa bayan hawan jini, yana haifar da ruwa da riƙewar sodium.Wannan samfurin baya tsoma baki tare da motsin motsin sinadarai na sinadarai, don haka hauhawar jini na orthostatic baya faruwa.Minoxidil magani ne da aka saba amfani da shi kuma mai inganci don maganin asarar gashi, amma tasirin sa na harhada magunguna da ƙwayoyin da aka yi niyya ba su bayyana sosai ba.A cikin 'yan shekarun nan, bincike ya nuna cewa Minoxidil na iya inganta ci gaban gashi ta hanyoyi masu zuwa.
Wani maganin baka da ake amfani da shi a asibiti don rage hawan jini
Minoxidil wani nau'i ne na maganin baka da ake amfani dashi don rage hawan jini a asibiti, wanda kuma aka sani da Changbaridine, piperazine enediamine, hypotenidine da Minlohemoidine.Yana da wakili na budewa na tashar tashar potassium, wanda zai iya shakatar da tsoka mai santsi kai tsaye kuma yana da tasiri mai ƙarfi na ƙananan jijiyoyi, rage juriya na gefe, dilatation na jini da hawan jini, amma ba shi da tasiri akan tasoshin girma, don haka zai iya inganta dawowar venous.A lokaci guda, fitarwar zuciya da bugun zuciya na iya ƙaruwa saboda ƙa'idodin reflex da ingantaccen tasirin mita, amma baya haifar da hauhawar jini na baya.Clinically amfani da magani refractory hauhawar jini da na koda hauhawar jini.Hakanan za'a iya amfani dashi don hauhawar jini mai tsanani tare da rashin amsawa ga sauran magungunan antihypertensive, amma yana buƙatar haɗa shi da diuretics don guje wa riƙewar ruwa da sodium.Lokacin da aka haɗe shi da magungunan β-blocking, ana iya ƙara tasirin sa kuma an rage halayen halayen.Ɗaya daga cikin illar amfani na dogon lokaci na Minoxidil da Chemicalbook shine gashin jiki na iya ƙara dan kadan tare da ci gaba da amfani da miyagun ƙwayoyi, kamar gashin hannu.Amma gabaɗaya a cikin iyakoki masu karɓuwa.Babban illolin da ke tattare da gudanarwar baki sun hada da karuwar nauyi da ƙananan kumburin gaɓoɓin da ke haifar da ruwa da riƙewar sodium, bugun zuciya da arrhythmia wanda ya haifar da tashin hankali na jijiya mai juyayi, da hirsuism.Babban mummunan halayen na shirye-shirye na Topical sune fushin fata, erythema, pruritus da sauran halayen dermatitis.Ko da yake adadin sha a cikin shirye-shiryen da ake yi yana da ƙananan ƙananan, ba za a iya yanke shawarar cewa zai iya yin tasiri a kan yanayin marasa lafiya da tarihin cututtukan zuciya ba.Marasa lafiya da cututtukan cerebrovascular, cututtukan zuciya da ba a haifar da hauhawar jini ba, cututtukan zuciya, angina pectoris, infarction myocardial, bugun pericardial, rashin aikin koda da sauran cututtuka dole ne a yi amfani da su a hankali, rashin lafiyar minoxidil da marasa lafiya pheochromocytoma ya kamata a hana su.
Lokacin aikawa: Janairu-06-2023