Nafarelin CAS: 76932-56-4 RS-94991-298 Nasanyl
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Amfani
Nafarelin, wanda aka sayar a ƙarƙashin sunayen kasuwanci irin su Synarel, maganin gonadotropin ne mai sakin hormone agonist (GnRH agonist) da ake amfani da shi don magance endometriosis da kuma balaga.Hakanan ana amfani dashi don magance fibroids na mahaifa, sarrafa haɓakar ovarian yayin haɗewar in vitro (IVF), da kuma wani ɓangare na maganin hormone na giciye.Ana amfani da miyagun ƙwayoyi azaman feshin hanci sau biyu zuwa uku a rana.
Abubuwan da ke haifar da nafarelin suna da alaƙa da rashi na hormone jima'i kuma sun haɗa da alamun ƙananan matakan testosterone da ƙananan matakan estrogen, irin su zafi mai zafi, lalata jima'i, atrophy na farji, da osteoporosis.Nafarelin shine agonist hormone mai sakin gonadotropin (GnRH agonist) wanda ke aiki ta hanyar hana gonads samar da hormones na jima'i.Yana iya rage matakan hormone jima'i a cikin duka jinsin da kashi 95 cikin dari.Nafarelin shine peptide wanda shine analog na GnRH.
An ƙaddamar da Nafarelin don amfani da magani a cikin 1990. Ana amfani da shi sosai a duniya, ciki har da Arewacin Amirka, Turai, da sauran sassan duniya.Magungunan yana ɗaya daga cikin analogues guda biyu na GnRH da ake amfani da su a likitanci waɗanda ake samu azaman feshin hanci, ɗayan kuma shine Bucherelin.
Amfanin likita:
An amince da Nafarelin don magance endometriosis da balaga.Ana kuma amfani da shi don maganin fibroids na mahaifa.Ana amfani da miyagun ƙwayoyi don sarrafa karfin ovarian yayin hadi in vitro (IVF).Ana amfani da Nafarelin azaman mai hana balaga ga matasa transgender kuma don kashe matakan testosterone a cikin matan transgender.Ana iya amfani da Nafarelin don magance hypertrichosis da polycystic ovary syndrome ta hanyar rage gonadotropin da matakan androgen.Yana da tasiri wajen magance hyperplasia na prostatic mara kyau