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Babban Pharma API CAS14769-73-4 Hydrochloride Levamisole Base

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  • Sunan gama gari:Levamisole
  • Lambar CAS:14769-73-4
  • MF:Saukewa: C11H12N2S
  • MW:204.29
  • EINECS:238-836-5
  • Wurin narkewa:60-61.5°
  • alfa:D25 -85.1° (c = 10 a cikin chloroform)
  • Wurin tafasa:344.4 ± 45.0 °C (An annabta)
  • yawa:1.32± 0.1 g/cm3 (An annabta)
  • ma'ajiyar yanayi:An rufe shi a bushe, 2-8 ° C
  • pka:10.00± 0.40 (An annabta)
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  • Cikakken Bayani

    Tags samfurin

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    Bayanan asali

    CAS14769-73-4 Hydrochloride Levamisole Base

    Ma'anarsa

    A 6-phenyl-2,3,5,6-tetrahydroimidazo [2,1-b] [1,3] thiazole wanda ke da tsarin S.Ana amfani da shi (gaba ɗaya azaman gishiri na monohydrochloride) don magance cututtukan tsutsotsi na tsutsotsi a cikin aladu, tumaki da shanu kuma a da ana amfani dashi a cikin huma s azaman adjuvant ga chemotherapy don maganin cututtukan daji daban-daban.Hakanan ana amfani dashi sosai azaman zinare ga kwakwa.

    Alamu

    Levamisole (Ergamisol) maganin antiparasitic ne wanda aka samo don haɓaka aikin T-cell da rigakafi na salula.Magungunan yana inganta rayuwar marasa lafiya tare da ciwon daji na launin fata lokacin da aka hade tare da 5-fluorouracil;ba a san tsarin wannan hulɗar ba.Levamisole ba shi da aikin antitumor akan kafaffen ko ciwon daji na metastatic kuma ba a same shi da amfani a cikin maganin cutar kansa ba banda ciwon daji na colorectal.

    Babban illar levamisole shine tashin zuciya da rashin ƙarfi.An kuma ga kurajen fata, ƙaiƙayi, alamun mura, da zazzaɓi.

    Alamu

    Levamisole (Ergamisol) an samo asali ne azaman maganin antihelminthic.Yana ƙarfafa tasirin stimulatory na antigens, mitogens, lymphokines, da abubuwan chemotactic akan lymphocytes, granulocytes, da macrophages.An nuna shi yana ƙara rigakafi mai shiga tsakani T cell.

    An yi amfani da Levamisole cikin nasara wajen magance cututtuka masu tsanani.Hakanan an yarda dashi don amfani tare da fluorouracil a cikin maganin ciwon daji na colorectal.

    CAS 94-15-5
    Levamisole
    Levamisole

    Amfani

    Amfani Mai gyara martanin halittu.

    Amfani   Ana amfani da Levamisole don yanayi na farko da na biyu na immunodeficient, cututtuka na autoimmune, cututtuka na yau da kullum da kuma sake faruwa, babban hanji adenocarcinoma, helmintosis, da rheumatoid arthritis.Synonyms na wannan magani sune decaris, tetramizole, da sauransu.

    Levimasole kuma magani ne na zaɓi don ascardiasis.Yawancin bincike sun nuna cewa kashi ɗaya na levamisole yana warkarwa daga 90 zuwa 100% na marasa lafiya tare da ascardiasis, musamman wadanda suka kamu da A. duodenale.Yana da ƙarancin tasiri akan ancylostomiasis da strongyloidiasis.Duk da haka, ba shi da tasiri a kan N. americanus.Da alama yana da tasirin gangliostimulating akan ƙwayoyin cuta a cikin yankuna na parasympathetic da na tausayi.Bugu da ƙari, ana zaton cewa wannan magani yana da tasirin immunomodulatory akan kwayoyin halitta.Synonyms na wannan magani sune decaris, solacil, ergamisol, tramisol, immunol, da sauransu.

    Amfanin asibiti

    Ascariasis Hooworm kamuwa da cuta

    An yi amfani da Levamisole a cikin cututtukan cututtuka na rheumatoid da wasu wasu yanayi waɗanda aka ce sun amsa ga aikin immunomodulatory.

    Ayyukan warkewa

    Anti kumburi

    Ayyukan antimicrobial

    Babban aikinsa ya sabawa Asc.lumbricoides da hookworms.Tsutsotsi sun shanye kuma suna wucewa a cikin najasa cikin 'yan sa'o'i.

    Aikace-aikacen Magunguna

    L-isomer na tetramisole, samuwa a matsayin monohydrochloride.D-isomer ba shi da aikin anthelmintic.Yana da narkewa sosai a cikin ruwa kuma yana da kwanciyar hankali a cikin bushewa.

    Hanyar aiki

    Levamisole yana da aikin immunomodulating.An yi imani da cewa yana tsara tsarin salon salula na tsarin rigakafi, kuma tsarin aikinsa na iya haɗawa da kunnawa da haɓaka haɓakar T-lymphocytes, ƙara yawan monocytes da kunna macrophages, kuma tare da ƙara yawan aiki da hemotaxis na neutrophylic. granulocytes.Levamisole kuma yana nuna aikin anthelmint.Hakanan yana ƙara ƙarfin juriya ga jiki gaba ɗaya kuma yana maido da canjin T-lymphocyte da aikin phagocyte.Hakanan yana iya cika aikin immunomodulatory ta hanyar ƙarfafa raunin rigakafi na salon salula, raunana ƙarfi mai ƙarfi, kuma ba shi da wani tasiri akan halayen al'ada.


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