GW-0742 SARMs Foda |GW610742 CAS 317318-84-6
Amfani
Don kiba, ciwon sukari, dyslipidemia da cututtukan zuciya da jijiyoyin jini magani na gwaji da ake nufi don sarrafa lipids da haɓaka matakin HDL, ko cholesterol mai kyau, a cikin jini.Ƙwararren tantanin halitta, thiazolyl fili wanda ke aiki a matsayin mai karfi, babban dangantaka, PPARδ agonist.Yana nuna zaɓi don PPARδ idan aka kwatanta da PPARA da PPARγ.Ba ya barin kowane aiki akan sauran makaman nukiliya ko waɗanda ba na nukiliya ba.An ba da rahoton ƙara yawan ƙwayar cholesterol da magana ABAC1 a cikin macrophages, fibroblasts, da ƙwayoyin hanji.
Cardarine yana amfani da 'yan wasa da ke fafatawa a wasanni daban-daban.Misali, 'yan wasa masu juriya na iya haɓaka juriyar motsa jiki ta hanyar tara wannan PPAR tare da maganin analog na AMP na AICAR, ko gudu cardarine solo.Sakamakon haka, za su sami babban ƙarfin isa ga RPM mafi girma yayin gudanar da su ba tare da bugun matsakaicin bugun zuciya ba.Wannan zai ba da damar mai gudu/masu keke/mai ninkaya su yaudari iyakar adadin zuciyarsu kuma su daɗe ba tare da yin iska ba, yin wannan tari ya zama makami mai ban mamaki don amfani da shi a wasannin juriya.A zahiri, daga gwaninta na sirri zan iya faɗi cewa cardarine na iya buga sama da daƙiƙa 30-45 kashe lokacin 5K idan aka yi amfani da shi har zuwa tseren.
Bayani
KEY KALMOMI: Rashin mai, inganta juriya, babu sakamako mai illa, mai gina jiki, maganin kiba da kuma taimakawa wajen riƙe kiba, yana ƙara yawan tsoka.
Cardarine (GW-501516) an haɗa shi a cikin nau'in SARMS, duk da haka a cikin tsari da ma'anar, shi ne PPAR modulator.A matsayin mai daidaitawa na PPAR, yana kunna furotin kinase mai kunnawa AMP kuma yana ƙarfafa ɗaukar glucose a cikin ƙwayar tsoka na kwarangwal.GW-501516 yana da damar iya juyar da matsalolin metabolism ta hanyar haɓaka oxidation fatty acid.Ana la'akari da shi azaman magani mai ƙarfi don kiba da sauran yanayi masu alaƙa.
GW501516 sunan Glaxo Wellcome magani ne (GW yana nufin kamfani kuma lambar ita ce ta samfurin).Hakanan ana kiransa GW-501,516, GW1516, GSK-516).Yana da PPARδ agonist mai karɓa wanda ba a ɗauka fiye da gwajin asibiti ba.Don haka an haramta shi a wasanni.Ya dace da wurare da dama a jerin, ciki har da musamman a matsayin "masu ƙiyayya mai ƙima mai haɓakawa mai karɓa (PPARδ) agonists (misali GW501516)".Amma kuma zai zo a ƙarƙashin sabon kama duk wani sashin "wadanda ba a yarda da su ba" wanda ke da nufin dakatar da duk wani magani mara izini da 'yan wasa ke amfani da su.
GW501516 (wanda aka fi sani da GW-501,516, GW1516, GSK-516) shine PPAR & agonist mai karɓa wanda aka ƙirƙira a cikin haɗin gwiwa tsakanin Ligand Pharmaceuticals da GlaxoSmithKline a cikin 1990s, an shigar da shi cikin ci gaban asibiti a matsayin ɗan takara na cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan cututtukan ƙwayoyin cuta , kuma an yi watsi da shi a shekara ta 2007 saboda gwajin dabbobi ya nuna cewa maganin yana haifar da ciwon daji da sauri a cikin sassa da yawa.
A cikin 2007 bincike da aka buga yana nuna cewa manyan allurai na GW501516 da aka ba wa mice sun inganta aikin jiki sosai;An tattauna aikin sosai a cikin shahararrun kafofin watsa labaru, kuma ya haifar da kasuwar baƙar fata ga dan takarar da kuma cin zarafin da 'yan wasa ke yi a matsayin magungunan kashe qwari.
Aikace-aikace
GW501516 na iya amfani da 'yan wasa azaman ergogenic aikin haɓaka magani wanda a halin yanzu ba a sarrafa shi ta hanyar ƙa'idodi ko gano ta daidaitattun gwaje-gwaje.Daya daga cikin manyan masu bincike daga binciken kan inganta juriya saboda haka ya kirkiro gwajin fitsari don gano maganin, kuma ya ba da shi ga kwamitin Olympics na kasa da kasa.
GW yana motsa shan glucose da kwarangwal tsoka.Yana ƙone mai ta hanyar ƙarfafa iskar oxygen da fatty acid.An ba da shawarar a matsayin yuwuwar maganin kiba saboda ƙarfinsa na narkewa da sauri.Har ila yau, an ce Cardarine yana ƙara HDL da matsakaita na 79% (cholesterol mai kyau) da rage LDL (mummunan cholesterol) a cikin gwaji na II na yanzu.GW 501516 shine PPARδ agonist.Waɗannan suna taimakawa haɓaka matakan HDL ɗinku daga ingantaccen bayanin mai jigilar cholesterol ABCA1.
GW yana motsa shan glucose da kwarangwal tsoka.Yana ƙone mai ta hanyar ƙarfafa iskar oxygen da fatty acid.An ba da shawarar a matsayin yuwuwar maganin kiba saboda ƙarfinsa na narkewa da sauri.Har ila yau, an ce Cardarine yana ƙara HDL da matsakaita na 79% (cholesterol mai kyau) da rage LDL (mummunan cholesterol) a cikin gwaji na II na yanzu.GW 501516 shine PPARδ agonist.Waɗannan suna taimakawa haɓaka matakan HDL ɗinku daga ingantaccen bayanin mai jigilar cholesterol ABCA1.
Marufi & Bayarwa
