GHRP-2/Pralmorelin CAS: 158861-67-7 d-ala-β- (2-naphthyl) -d-ala-trp-d-phe-lys amide

Pralmorelin (INN) (sunan kasuwanci GHRP Kaken 100; Tsohuwar lambar ci gaba suna KP-102, GPA-748, WAY-GPA-748), wanda kuma aka sani da pralmorelin hydrochloride (JAN) da pralmorelin dihydrochloride (USAN), kuma musamman, Girma Hormone mai sakin Peptide 2 (GHRP-2), mai sakatariyar hormone girma (GHS), ana amfani dashi azaman wakili na bincike kuma ana tallata shi a cikin nau'in tsari guda ɗaya ta Kaken Pharmaceutical na Japan don kimanta ƙarancin ƙarancin hormone girma (GHD).

Pralmorelin magani ne na peptide na roba tare da aikin baka.Musamman, shi ne analogue na methoxyenkephalin tare da jerin amino acid D-Ala-D -(β-naphthyl) -ala-trp-d-phe -Lys-NH 2. Yana aiki a matsayin auxin sakewa peptide / girma hormone secretin receptor (auxin). GHSR) agonist kuma shine nau'in magani na farko da aka gabatar a cikin asibitin.Gudanar da miyagun ƙwayoyi yana haɓaka matakan haɓakar ƙwayar plasma (GH) sosai kuma yana haifar da yunwa kuma yana ƙara yawan abinci a cikin mutane.

Ana kuma nazarin Pralmorelin don GHD da ɗan gajeren tsayi (pituitary dwarfism) kuma ya shiga gwajin gwaji na asibiti na II don waɗannan alamun, amma a ƙarshe bai taɓa yin kasuwa ba.Wannan na iya zama saboda ikon pramoline na ƙara matakan GH na plasma ya ragu sosai a cikin marasa lafiya na GHD fiye da na mutane masu lafiya