Chemical Material Anesthetics magunguna masu taimako CAS 59-46-1 PROCAINE
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Bayanan asali
Bayani
Procaine magani ne na gida tare da aikin para-amino.Hankali ya shafi ƙwararrun likitanci, hakori da kuma aikin likitan dabbobi.
Abubuwan Sinadarai
Gishirin hydrochloride na 2- (diethylamino) ethyl p-aminobenzoate (C13H21ClN2O2 ko N2C6H4COOCH2CH2NH(C2H5)2HCl) ana kiransa gabaɗaya azaman procaine.Kodayake PABA ester ba shi da narkewa a cikin ruwa, gishiri na hydrochloride yana narkewa sosai a cikin ruwa.
Amfani
1.Procaine (Novocain) galibi ana amfani dashi a cikin hakori ko hanyoyin likitanci waɗanda ke buƙatar saɓanin infiltration, toshe na gefe, ko toshewar kashin baya.
2.mai hana sodium channel
3. Procaine shine mai hana tashar sodium kuma mai hana nau'o'in matakai.
Amfani
Amfanin asibitiProcaine yana da sauri metabolized a cikin plasma ta hanyar cholinesterases kuma a cikin hanta ta hanyar ester hydrolysis ta hanyar pseudocholinesterase.Rabin rayuwar in vitroelimination kusan daƙiƙa 60 ne.Duk wani yanayin da ke rage ƙwayar cholinesterase zai iya ƙara haɓakawa zuwa procaine da yuwuwar guba.Za a iya samun aikin rage yawan ƙwayar cuta tare da rashi kwayoyin halitta, ciwon hanta, rashin lafiya, rashin abinci mai gina jiki, gazawar koda, konewa, na uku na ciki, da kuma bin aikin tiyata na zuciya.Ester hydrolysis yana samar da PABA, mahaɗan da ke da alhakin halayen rashin lafiyar da aka saba da su ga maganin sa barci.Procaine ba a yi amfani da topically saboda da ikon iya wucewa ta cikin lipid membranes da kuma samun amfani a matsayin anti-filtration wakili ga cutaneous ko mucous membranes, gagare hanyoyin.Hakanan ana amfani da Procaine don shingen jijiyoyi na gefe kuma azaman wakili na epidural don tantance cututtukan ciwon.